Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is
emerging as a powerful tool for investigating the distribution of molecules within biological …

The rapid development of high‐throughput technologies and computational frameworks
enables the examination of biological systems in unprecedented detail. The ability to study …

We have employed matrix deposition by sublimation for protein image analysis on tissue
sections using a hydration/recrystallization process that produces high-quality MALDI mass …

Imaging mass spectrometry (IMS) using matrix-assisted laser desorption ionization (MALDI)
is a new and effective tool for molecular studies of complex biological samples such as …

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a
powerful tool for investigating the distribution of proteins and small molecules within …

For decades, formaldehyde has been routinely used to cross‐link proteins in cells, tissue,
and in some instances, even entire organisms. Due to its small size, formaldehyde can …

Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …

A novel method for high‐throughput proteomic analysis of formalin‐fixed paraffin‐embedded
(FFPE) tissue microarrays (TMA) is described using on‐tissue tryptic digestion followed by …