Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …

This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

Developing synthetically useful enzymatic reactions that are not known in biochemistry and
organic chemistry is an important challenge in biocatalysis. Through the synergistic merger …

The chemical investigation of marine mollusks has led to the isolation of a wide variety of
bioactive metabolites, which evolved in marine organisms as favorable adaptations to …

Two new chlorinated fatty acid amides, columbamides D (1) and E (2), along with apratoxins
A and C and wewakazole, were isolated from the organic extract of a Moorea bouillonii …

NMR-and MS-guided fractionation of an extract of an Okeania sp. marine cyanobacterium,
collected from the Red Sea, led to the isolation of four new metabolites, including …

Residual complexity (RC) involves the impact of subtle but critical structural and biological
features on drug lead validation, including unexplained effects related to unidentified …

Dolastatin 16, a marine cyclic depsipeptide, was initially isolated from the sea hare
Dolabella Auricularia by Pettit et al. Due to the lack of information regarding its bioactivity …

Cyclic peptides are reported to have antibacterial, antifungal, and other bioactivities.
Orbitides are a class of cyclic peptides that are small, head-to-tail cyclized, composed of …

The total synthesis of dolastatin 16, a macrocyclic depsipeptide first isolated from the sea
hare Dolabella auricularia as a potential antineoplastic metabolite by Pettit et al., was …