[HTML][HTML] Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

[HTML][HTML] Collagen in wound healing

SS Mathew-Steiner, S Roy, CK Sen - Bioengineering, 2021 - mdpi.com
Normal wound healing progresses through inflammatory, proliferative and remodeling
phases in response to tissue injury. Collagen, a key component of the extracellular matrix …

Wound healing: from passive to smart dressings

M Farahani, A Shafiee - Advanced Healthcare Materials, 2021 - Wiley Online Library
The universal increase in the number of patients with nonhealing skin wounds imposes a
huge social and economic burden on the patients and healthcare systems. Although, the …

Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

All‐in‐one: multifunctional hydrogel accelerates oxidative diabetic wound healing through timed‐release of exosome and fibroblast growth factor

Y Xiong, L Chen, P Liu, T Yu, C Lin, C Yan, Y Hu… - Small, 2022 - Wiley Online Library
The treatment of diabetic wounds remains a major challenge in clinical practice, with chronic
wounds characterized by multiple drug‐resistant bacterial infections, angiopathy, and …

Microenvironment‐based diabetic foot ulcer nanomedicine

F Huang, X Lu, Y Yang, Y Yang, Y Li, L Kuai… - Advanced …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFU), one of the most serious complications of diabetes, are essentially
chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial …

[HTML][HTML] Epithelial-mesenchymal transition (EMT): the type-2 EMT in wound healing, tissue regeneration and organ fibrosis

GD Marconi, L Fonticoli, TS Rajan, SD Pierdomenico… - Cells, 2021 - mdpi.com
The epithelial–mesenchymal transition (EMT) is an essential event during cell development,
in which epithelial cells acquire mesenchymal fibroblast-like features including reduced …

[HTML][HTML] Macrophages as a therapeutic target to promote diabetic wound healing

M Sharifiaghdam, E Shaabani, R Faridi-Majidi… - Molecular Therapy, 2022 - cell.com
It is well‏‏ established that macrophages are key regulators of wound healing, displaying
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …

Double cross‐linked biomimetic hyaluronic acid‐based hydrogels with thermo‐stimulated self‐contraction and tissue adhesiveness for accelerating post‐wound …

Y Zhao, B Yi, J Hu, D Zhang, G Li… - Advanced Functional …, 2023 - Wiley Online Library
When skin trauma occurs, rapid achievement of the post‐wound closure is required to
prevent microbial invasion, inhibit scar formation and promote wound healing. To develop a …

A review of current advancements for wound healing: Biomaterial applications and medical devices

X Deng, M Gould, MA Ali - Journal of Biomedical Materials …, 2022 - Wiley Online Library
Wound healing is a complex process that is critical in restoring the skin's barrier function.
This process can be interrupted by numerous diseases resulting in chronic wounds that …