Stem cells and angiogenesis: implications and limitations in enhancing chronic diabetic foot ulcer healing

V Rai, R Moellmer, DK Agrawal - Cells, 2022 - mdpi.com
Nonhealing diabetic foot ulcers (DFUs) are a continuing clinical issue despite the improved
treatment with wound debridement, off-loading the ulcer, medication, wound dressings, and …

Clinical and patient‐reported outcomes of tissue engineering strategies for periodontal and peri‐implant reconstruction

L Tavelli, S Barootchi, G Rasperini… - Periodontology …, 2023 - Wiley Online Library
Scientific advancements in biomaterials, cellular therapies, and growth factors have brought
new therapeutic options for periodontal and peri‐implant reconstructive procedures. These …

Single‐cell and spatial transcriptomics decodes Wharton's jelly‐derived mesenchymal stem cells heterogeneity and a subpopulation with wound repair signatures

P Chen, S Tang, M Li, D Wang, C Chen… - Advanced …, 2023 - Wiley Online Library
The highly heterogeneous characteristics of Wharton's jelly mesenchymal stem cells (WJ‐
MSCs) may be responsible for the poor clinical outcomes and poor reproducibility of …

Anti-viral activities of umbilical cord mesenchymal stem cell-derived small extracellular vesicles against human respiratory viruses

SJ Oh, EN Lee, JH Park, JK Lee, GJ Cho… - Frontiers in Cellular …, 2022 - frontiersin.org
The endemic and pandemic caused by respiratory virus infection are a major cause of
mortality and morbidity globally. Thus, broadly effective antiviral drugs are needed to treat …

[HTML][HTML] Human umbilical cord mesenchymal stem cells in diabetes mellitus and its complications: applications and research advances

L Li, J Li, H Guan, H Oishi, S Takahashi… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Diabetes mellitus and its complications pose a major threat to global health and affect the
quality of life and life expectancy of patients. Currently, the application of traditional …

[HTML][HTML] Allogeneic transplantation of epidermal cell sheets followed by endoscopic submucosal dissection to prevent severe esophageal stricture in a porcine model

S Kobayashi, N Kanai, M Yamato, S Eguchi - Regenerative Therapy, 2022 - Elsevier
Introduction Endoscopic submucosal dissection (ESD) is a minimally invasive treatment for
early esophageal cancer. However, large mucosal defects after esophageal ESD result in …

Therapeutic potential in wound healing of allogeneic use of equine umbilical cord mesenchymal stem cells

A Iribarne, MB Palma, L Andrini, F Riccillo… - International Journal of …, 2024 - mdpi.com
Wound healing after skin injury is a complex process, particularly in equines where leg
wounds are prevalent and their repair is complicated due to the anatomical characteristics …

Nerve guide conduits promote nerve regeneration under a combination of electrical stimulation and RSCs combined with stem cell differentiation

F Zhang, L Nan, J Fang, L Liu, B Xu, X Jin… - Journal of Materials …, 2024 - pubs.rsc.org
Nerve guide conduits (NGCs) offer a promising alternative to traditional tools for
regenerating peripheral nerves. The efficacy of nerve regeneration and functional recovery …

Therapeutic effect and study of human umbilical cord blood mononuclear cells in patients with ischaemic bowel disease

X Cai, Y Li, F Gao, B Muhammad, H Yang - Scientific Reports, 2024 - nature.com
Ischaemic bowel disease (ICBD) is a group of intestinal ischaemia syndromes caused by
various aetiologies of reduced intestinal blood flow or vascular occlusion. ICBD can present …

Injection of stem cells derived from allogeneic adipose tissue, a new strategy for the treatment of diabetic wounds

R Izadi, SH Hejazi, S Bahramikia - Journal of Diabetes and its …, 2023 - Elsevier
A diabetic wound is one of the major complications of Diabetes mellitus. Considering the
impact of these wounds on the health and quality of life of diabetic patients, the need for a …