Bile acids are amphipathic, detergent molecules. The detergent effects of di-α-hydroxy-bile
acids are relevant to several colonic diseases. The aims were to review the concentrations …

Bile acids (BA) are amphipathic molecules originating from cholesterol in the liver and from
microbiota-driven biotransformation in the colon. In the gut, BA play a key role in fat …

Irritable bowel syndrome with predominant diarrhea (IBS-D) and functional diarrhea (FD) are
disorders of gut–brain interaction characterized by recurring symptoms which have a serious …

Background Bile acids are central to enterohepatic signaling pathways activated through
natural receptors, farnesoid X receptor [FXR mediates synthesis of fibroblast growth factor …

Bile acid diarrhea (BAD) is characterized by increased frequency of bowel movements,
looser stool consistency, urgency, and need for proximity to toilet facilities owing to the …

Introduction Bile acid diarrhea (BAD) commonly causes chronic diarrhea. Symptoms may be
mistaken for disorders of gut brain interaction. Due to the lack of widely available diagnostic …

Background & Aims Bile acid sequestrants (BAS) may be a treatment in microscopic colitis
(MC), but efficacy data are limited. We evaluated the effectiveness of BAS in MC and …

Bile acid malabsorption (BAM) is an important disorder of digestive pathophysiology as it
generates chronic diarrhoea. This condition originates from intricate pathways involving bile …

Background Many patients with quiescent inflammatory bowel disease (IBD) suffer from
irritable bowel syndrome (IBS)‐like symptoms. Although these symptoms cause significant …

(IPAA) for intractable ulcerative colitis (UC), about 50% of patients experience pouchitis. 1
The prevalence of pouchitis is 5-fold higher in UC than in patients who undergo the same …