Inwardly rectifying potassium channels: their structure, function, and physiological roles

H Hibino, A Inanobe, K Furutani… - Physiological …, 2010 - journals.physiology.org
Inwardly rectifying K+ (Kir) channels allow K+ to move more easily into rather than out of the
cell. They have diverse physiological functions depending on their type and their location …

[HTML][HTML] Mitochondrial channels: ion fluxes and more

I Szabo, M Zoratti - Physiological reviews, 2014 - journals.physiology.org
The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

KATP Channels in the Cardiovascular System

MN Foster, WA Coetzee - Physiological reviews, 2016 - journals.physiology.org
KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …

Molecular Diversity of K+ Channels

WA Coetzee, Y Amarillo, J Chiu, A Chow… - Annals of the New …, 1999 - Wiley Online Library
K+ channel principal subunits are by far the largest and most diverse of the ion channels.
This diversity originates partly from the large number of genes coding for K+ channel …

KATP channels as molecular sensors of cellular metabolism

CG Nichols - Nature, 2006 - nature.com
In responding to cytoplasmic nucleotide levels, ATP-sensitive potassium (KATP) channel
activity provides a unique link between cellular energetics and electrical excitability. Over …

Activating Mutations in the ABCC8 Gene in Neonatal Diabetes Mellitus

AP Babenko, M Polak, H Cavé, K Busiah… - … England Journal of …, 2006 - Mass Medical Soc
Background The ATP-sensitive potassium (KATP) channel, composed of the beta-cell
proteins sulfonylurea receptor (SUR1) and inward-rectifying potassium channel subunit Kir6 …

ATP-sensitive potassium channelopathies: focus on insulin secretion

FM Ashcroft - The Journal of clinical investigation, 2005 - Am Soc Clin Investig
ATP-sensitive potassium (KATP) channels, so named because they are inhibited by
intracellular ATP, play key physiological roles in many tissues. In pancreatic β cells, these …

A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane KATP channels

N Zerangue, B Schwappach, YN Jan, LY Jan - Neuron, 1999 - cell.com
Proper ion channel function often requires specific combinations of pore-forming α and
regulatory β subunits, but little is known about the mechanisms that regulate the surface …

Molecular biology of adenosine triphosphate-sensitive potassium channels

L Aguilar-Bryan, J Bryan - Endocrine reviews, 1999 - academic.oup.com
Molecular Biology of Adenosine Triphosphate-Sensitive Potassium Channels* | Endocrine
Reviews | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals …

Potassium channels: molecular defects, diseases, and therapeutic opportunities

CC Shieh, M Coghlan, JP Sullivan… - Pharmacological …, 2000 - ASPET
Potassium channels play important roles in vital cellular signaling processes in both
excitable and nonexcitable cells. Over 50 human genes encoding various K+ channels have …