The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities

A Afrasiabi, C Ahlenstiel… - Clinical & …, 2023 - Wiley Online Library
Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease, characterised
by the demyelination of neurons in the central nervous system. Whilst it is unclear what …

B cells in multiple sclerosis and virus-induced neuroinflammation

R Chunder, V Schropp, S Kuerten - Frontiers in neurology, 2020 - frontiersin.org
Neuroinflammation can be defined as an inflammatory response within the central nervous
system (CNS) mediated by a complex crosstalk between CNS-resident and infiltrating …

Gender and the sex hormone estradiol affect multiple sclerosis risk gene expression in epstein-barr virus-infected B cells

JT Keane, A Afrasiabi, SD Schibeci, N Fewings… - Frontiers in …, 2021 - frontiersin.org
Multiple Sclerosis (MS) is a complex immune-mediated disease of the central nervous
system. Treatment is based on immunomodulation, including specifically targeting B cells. B …

KARAJ: An Efficient Adaptive Multi-Processor Tool to Streamline Genomic and Transcriptomic Sequence Data Acquisition

M Labani, A Beheshti, NH Lovell… - International Journal of …, 2022 - mdpi.com
Here we developed KARAJ, a fast and flexible Linux command-line tool to automate the end-
to-end process of querying and downloading a wide range of genomic and transcriptomic …

[PDF][PDF] Fatores ambientais envolvidos na Fisiopatologia da Esclerose Múltipla: uma revisão bibliográfica Environmental factors involved in the Pathophysiology of …

LG Carvalho, LR Fogari, MEL Caparroz… - Brazilian Journal of …, 2022 - academia.edu
Introdução: Esclerose múltipla (EM) é uma doença inflamatória crônica, desmielinizante e
autoimune; sendo mais incidente geograficamente em altas latitudes. Sendo sua etiologia …

Fatores ambientais envolvidos na fisiopatologia da Esclerose múltipla: uma revisão bibliográfica

LG Carvalho, LR Fogari… - Brazilian Journal of …, 2023 - ojs.brazilianjournals.com.br
Introdução: Esclerose múltipla (EM) é uma doença inflamatória crônica, desmielinizante e
autoimune; sendo mais incidente geograficamente em altas latitudes. Sendo sua etiologia …

The Role of Epigenetics in Multiple Sclerosis Development, Progression and Treatment

E Ewing - 2020 - search.proquest.com
The overall aim of this thesis was to determine epigenetic changes in peripheral immune
cells from Multiple Sclerosis (MS) patients. MS is a chronic inflammatory neurodegenerative …