An updated review on marine anticancer compounds: The use of virtual screening for the discovery of small-molecule cancer drugs

V Ruiz-Torres, JA Encinar, M Herranz-Lopez… - Molecules, 2017 - mdpi.com
Marine secondary metabolites are a promising source of unexploited drugs that have a wide
structural diversity and have shown a variety of biological activities. These compounds are …

Natural ingredient-based polymeric nanoparticles for cancer treatment

KH Wong, A Lu, X Chen, Z Yang - Molecules, 2020 - mdpi.com
Cancer is a global health challenge. There are drawbacks to conventional chemotherapy
such as poor bioavailability, development of drug resistance and severe side effects. Novel …

Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

AE Ekkelenkamp, MR Elzes, JFJ Engbersen… - Journal of Materials …, 2018 - pubs.rsc.org
Water-soluble, nano-sized crosslinked polymer networks, or nanogels, are delivery vehicles,
which have highly interesting properties for therapeutic delivery and imaging. Nanogels may …

Biomimetic bacterial membrane vesicles for drug delivery applications

S Fazal, R Lee - Pharmaceutics, 2021 - mdpi.com
Numerous factors need to be considered to develop a nanodrug delivery system that is
biocompatible, non-toxic, easy to synthesize, cost-effective, and feasible for scale up over …

Marine anticancer drugs and their relevant targets: a treasure from the ocean

M Nigam, HAR Suleria, MH Farzaei… - DARU Journal of …, 2019 - Springer
Marine organisms comprising animals and plants are wealthiest sources of bioactive
compounds possessing various pharmacological properties specifically: free radical …

Nanomedicines guided nanoimaging probes and nanotherapeutics for early detection of lung cancer and abolishing pulmonary metastasis: critical appraisal of newer …

X Gao, L Guo, J Li, HE Thu, Z Hussain - Journal of Controlled Release, 2018 - Elsevier
Lung cancer (LC) is the second most prevalent type of cancer and primary cause of mortality
among both men and women, worldwide. The most commonly employed diagnostic …

Dual delivery of BMP2 and IGF1 through injectable hydrogel promotes cranial bone defect healing

YB Park, S Lin, Y Bai, S Moeinzadeh, S Kim… - … Engineering Part A, 2022 - liebertpub.com
Critical-sized cranial bone defect remains a great clinical challenge. With advantages in
regenerative medicine, injectable hydrogels incorporated with bioactive molecules show …

Gelatin nanoparticles for targeted dual drug release out of alginate-di-aldehyde-gelatin gels

S Schrade, L Ritschl, R Süss, P Schilling… - Gels, 2022 - mdpi.com
The aim of the present work was to develop a dual staged drug release of an antibiotic
(clindamycin) and a growth factor: bone morphogenetic protein-2 (BMP-2) from a …

Cross-linked porous gelatin microparticles with tunable shape, size, and porosity

R Gelli, G Mugnaini, T Bolognesi, M Bonini - Langmuir, 2021 - ACS Publications
Gelatin particles are relevant to many applications in the biomedical field due to their
excellent biocompatibility and versatility. When prepared by double emulsion methods …

Development of Ce-doped TiO2 activated by X-ray irradiation for alternative cancer treatment

CC Yang, YJ Sun, PH Chung, WY Chen… - Ceramics …, 2017 - Elsevier
Photodynamic therapy (PDT) is limited by its penetration depth because of the selection of
photosensitizer and light source. In this study, Ce-doped TiO 2 (TiO 2: Ce) was synthesized …