Bone biology: insights from osteogenesis imperfecta and related rare fragility syndromes

R Besio, CW Chow, F Tonelli, JC Marini… - The FEBS …, 2019 - Wiley Online Library
The limited accessibility of bone and its mineralized nature have restricted deep
investigation of its biology. Recent breakthroughs in identification of mutant proteins …

Nell-1 is a key functional modulator in osteochondrogenesis and beyond

C Li, X Zhang, Z Zheng, A Nguyen… - Journal of Dental …, 2019 - journals.sagepub.com
Neural EGFL-like 1 (Nell-1) is a well-studied osteogenic factor that has comparable
osteogenic potency with the Food and Drug Administration–approved bone morphogenic …

Association of early childhood caries with bitter taste receptors: A meta-analysis of genome-wide association studies and transcriptome-wide association study

E Orlova, T Dudding, JM Chernus, RN Alotaibi… - Genes, 2022 - mdpi.com
Although genetics affects early childhood caries (ECC) risk, few studies have focused on
finding its specific genetic determinants. Here, we performed genome-wide association …

Dental follicle cells participate in tooth eruption via the RUNX2-MiR-31-SATB2 loop

J Ge, S Guo, Y Fu, P Zhou, P Zhang… - Journal of dental …, 2015 - journals.sagepub.com
Cleidocranial dysplasia (CCD) is characterized by the runt-related transcription factor 2
(RUNX2) mutation, which results in delayed tooth eruption due to disturbed functions of …

Crispr-Cas9 engineered osteogenesis imperfecta type V leads to severe skeletal deformities and perinatal lethality in mice

F Rauch, Y Geng, L Lamplugh, B Hekmatnejad… - Bone, 2018 - Elsevier
Osteogenesis imperfecta (OI) type V is caused by an autosomal dominant mutation in the
IFITM5 gene, also known as BRIL. The c.-14C> T mutation in the 5'UTR of BRIL creates a …

Genetic comparison of stemness of human umbilical cord and dental pulp

CM Kang, H Kim, JS Song, BJ Choi… - Stem cells …, 2016 - Wiley Online Library
This study focuses on gene expression patterns and functions in human umbilical cord (UC)
and dental pulp (DP) containing mesenchymal stem cells (MSCs). DP tissues were collected …

Cyclic tensile force-upregulated IL6 increases MMP3 expression by human periodontal ligament cells

Y Tantilertanant, J Niyompanich, V Everts… - Archives of Oral …, 2019 - Elsevier
Objective Cyclic tensile force (CTF) modulates physiological responses of periodontal
ligament (PDL) cells. PDL cells are mechanosensitive and are able to maintain tissue …

Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression

HJ Schulten, D Hussein, F Al-Adwani, S Karim… - PloS one, 2016 - journals.plos.org
Meningiomas are the most common primary brain tumors bearing in a minority of cases an
aggressive phenotype. Although meningiomas are stratified according to their histology and …

Differential expression of extracellular matrix and adhesion molecules in fetal-origin amniotic epithelial cells of preeclamptic pregnancy

MS Kim, JH Yu, MY Lee, AL Kim, MH Jo, MG Kim… - PLoS …, 2016 - journals.plos.org
Preeclampsia is a common disease that can occur during human pregnancy and is a
leading cause of both maternal and neonatal morbidity and mortality. Inadequate …

8q21. 11 microdeletion in two patients with syndromic peters anomaly

H Happ, KF Schilter, E Weh, LM Reis… - American Journal of …, 2016 - Wiley Online Library
Peters anomaly is a form of anterior segment dysgenesis characterized by central ocular
opacity and corneo‐lenticular adhesions. Isolated and syndromic Peters anomaly can be …