A Synopsis of Hepatitis C Virus Treatments and Future Perspectives

C Medina, AH García, FI Crespo, FI Toro… - Current Issues in …, 2023 - mdpi.com
Hepatitis C virus (HCV) infection is a worldwide public health problem. Chronic infection with
HCV can lead to liver cirrhosis or cancer. Although some immune-competent individuals can …

Vitamin D role in hepatitis B: focus on immune system and genetics mechanism

A Asghari, F Jafari, M Jameshorani, H Chiti, M Naseri… - Heliyon, 2022 - cell.com
Abstract According to the World Health Organization (WHO) report, viral hepatitis has been a
problem in human society. Vitamins play a significant role in preventing the …

Single nucleotide polymorphisms in INFL3-INFL4 region are associated with fibrosis and cirrhosis in Egyptian patients with chronic hepatitis C

K Thabit, A Bkeet, E Abdelhalem, A Sharaf… - Journal of advanced …, 2023 - journals.ekb.eg
Genetic variables have a notable and polygenic impact on the incidence and development
of hepatic fibrosis and cirrhosis in individuals with chronic hepatitis C (CHC). Genetic …

IFNL4 haplotype, linkage disequilibrium and their influence on virological response to hepatitis C virus infection in Indian population

N Roy, C Prasad, A Kumar, K Mondol, K Jain, R Yadav… - VirusDisease, 2019 - Springer
Type III interferon (IFNs) encoded by IFN lambda (IFNL) genes induce antiviral activity. The
IFNL clusters include IFNL1/IL29, IFNL2/IL28A, IFNL3/IL28B and IFNL4 genes. The single …

The role of hepatic progenitor cells in predicting response to therapy in Egyptian patients with chronic hepatitis C, genotype 4

TEA Helal, NA Radwan, HA Mahmoud, AME Zaki… - African Health …, 2019 - ajol.info
Background: Interferon therapy is used as a line of treatment of chronic hepatitis C virus
(HCV) in several areas of the world including Egypt. Objective: Our aim was to investigate …

Influence of IL28B gene polymorphisms on PegINF-RBV-mediated HCV clearance in HIV-HCV co-infected patients: A meta-analysis

N Kumar, SS Prabhu, I Monga, I Banerjee - Meta Gene, 2021 - Elsevier
Background Previous studies suggested, variations in the IL28B gene can serve as
predictors of sustained and rapid virological responses (SVR and RVR) in the treatment of …