Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)‐driven Complement‐mediated Diseases
BG Gibson, TE Cox, KJ Marchbank - Immunological Reviews, 2023 - Wiley Online Library
This review aimed to capture the key findings that animal models have provided around the
role of the alternative pathway and amplification loop (AP/AL) in disease. Animal models …
role of the alternative pathway and amplification loop (AP/AL) in disease. Animal models …
Use of 31P magnetisation transfer magnetic resonance spectroscopy to measure ATP changes after 670 nm transcranial photobiomodulation in older adults
Mitochondrial function declines with age, and many pathological processes in
neurodegenerative diseases stem from this dysfunction when mitochondria fail to produce …
neurodegenerative diseases stem from this dysfunction when mitochondria fail to produce …
Watching the human retina breath in real time and the slowing of mitochondrial respiration with age
The retina has the greatest metabolic demand in the body particularly in dark adaptation
when its sensitivity is enhanced. This requires elevated level of perfusion to sustain …
when its sensitivity is enhanced. This requires elevated level of perfusion to sustain …
Near infrared spectroscopy reveals instability in retinal mitochondrial metabolism and haemodynamics with blue light exposure at environmental levels
P Kaynezhad, R Fosbury, C Hogg… - Journal of …, 2022 - Wiley Online Library
Abstract Blue light (~ 400‐470 nm) is considered potentially detrimental to the retina but is
present in natural environmental light. Mitochondrial density is highest in the retina, and they …
present in natural environmental light. Mitochondrial density is highest in the retina, and they …
Optically generated droplet beams improve optoacoustic imaging of choroid thickness as an Alzheimer's disease biomarker
Optoacoustic microscopy faces a restricted depth of field attributed to the tightly focused
Gaussian beam excitation. This limitation poses challenges in capturing high-resolution …
Gaussian beam excitation. This limitation poses challenges in capturing high-resolution …
[HTML][HTML] The role of neuroglobin in retinal hemodynamics and metabolism: A real-time study
Purpose: In this study, we used broadband near-infrared spectroscopy, a non-invasive
optical technique, to investigate in real time the possible role of neuroglobin in retinal …
optical technique, to investigate in real time the possible role of neuroglobin in retinal …
A Ray of Light Against Age Related Neurodegeneration
Mitochondrial function declines with age and many pathological processes of
neurodegenerative diseases stem from this dysfunction when mitochondria fail to produce …
neurodegenerative diseases stem from this dysfunction when mitochondria fail to produce …
[HTML][HTML] Watching the human retina breath in real time; the slowing of mitochondrial respiration with age in dark adaptation
The retina has the greatest metabolic demand in the body particularly in dark adaptation
when its sensitivity is enhanced. This requires an elevated levels of perfusion to sustain …
when its sensitivity is enhanced. This requires an elevated levels of perfusion to sustain …
Investigating the biomechanics and biochemistry underlying MRI measures of neuronal function
F Hauge Torkelsen - 2022 - etheses.whiterose.ac.uk
This thesis investigates the biophysical mechanisms underlying functional magnetic
resonance imaging (fMRI) measures of brain activity. Diffusion-weighted fMRI (DWfMRI) has …
resonance imaging (fMRI) measures of brain activity. Diffusion-weighted fMRI (DWfMRI) has …