With the growing problem of the emergence of antibiotic-resistant bacteria, the search for
alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …

Defensins have been long recognized as natural antimicrobial peptides, but they also
possess diverse and versatile immune functions. Defensins can both induce inflammation …

Extravasation of polymorphonuclear leukocytes (PMNs) to the site of inflammation precedes
a second wave of emigrating monocytes. That these events are causally connected has …

The emergence of infections caused by multi-drug resistant (MDR) pathogens pose a major
burden to modern healthcare. Exacerbating this issue is the substantial decline in …

The antimicrobial peptide LL-37 is the only known member of the cathelicidin family of
peptides expressed in humans. LL-37 is a multifunctional host defense molecule essential …

In acute inflammation, infiltrating polymorphonuclear leukocytes (also known as PMNs)
release preformed granule proteins having multitudinous effects on the surrounding …

Polymorphonuclear leukocytes (PMNs) release the contents of granules during their
migration to inflammatory sites. On liberation from the first leukocyte to enter injured tissue …

Three‐dimensional (3D) cancer models are overlooking the scientific landscape with the
primary goal of bridging the gaps between two‐dimensional (2D) cell lines, animal models …

Human defensins, which are small cationic peptides produced by neutrophils and epithelial
cells, form two genetically distinct alpha and beta subfamilies. They are involved in innate …

The innate immune system mounts the first host response to pathogens. Because α-
defensins, which are cationic antimicrobial peptides of polymorphonuclear neutrophils and …