Tumour burden and efficacy of immune-checkpoint inhibitors
FG Dall'Olio, A Marabelle, C Caramella… - Nature reviews Clinical …, 2022 - nature.com
Accumulating evidence suggests that a high tumour burden has a negative effect on
anticancer immunity. The concept of tumour burden, simply defined as the total amount of …
anticancer immunity. The concept of tumour burden, simply defined as the total amount of …
Tumor burden and immunotherapy: impact on immune infiltration and therapeutic outcomes
SI Kim, CR Cassella, KT Byrne - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy has revolutionized the treatment landscape in medical oncology, but
its efficacy has been variable across patients. Biomarkers to predict such differential …
its efficacy has been variable across patients. Biomarkers to predict such differential …
The oligometastatic spectrum in the era of improved detection and modern systemic therapy
Metastases remain the leading cause of cancer-related mortality. The oligometastasis
hypothesis postulates that a spectrum of metastatic spread exists and that some patients …
hypothesis postulates that a spectrum of metastatic spread exists and that some patients …
Predicting pathological highly invasive lung cancer from preoperative [18F]FDG PET/CT with multiple machine learning models
Purpose The efficacy of sublobar resection of primary lung cancer have been proven in
recent years. However, sublobar resection for highly invasive lung cancer increases local …
recent years. However, sublobar resection for highly invasive lung cancer increases local …
Comprehensive scientometrics and visualization study profiles lymphoma metabolism and identifies its significant research signatures
SB Guo, DQ Pan, N Su, MQ Huang, ZZ Zhou… - Frontiers in …, 2023 - frontiersin.org
Background There is a wealth of poorly utilized unstructured data on lymphoma metabolism,
and scientometrics and visualization study could serve as a robust tool to address this issue …
and scientometrics and visualization study could serve as a robust tool to address this issue …
[HTML][HTML] Combination of radiation therapy, bempegaldesleukin, and checkpoint blockade eradicates advanced solid tumors and metastases in mice
AA Pieper, AL Rakhmilevich… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Background Current clinical trials are using radiation therapy (RT) to enhance an antitumor
response elicited by high-dose interleukin (IL)-2 therapy or immune checkpoint blockade …
response elicited by high-dose interleukin (IL)-2 therapy or immune checkpoint blockade …
Predictive biomarkers for immune-checkpoint inhibitor treatment response in patients with hepatocellular carcinoma
JH Ji, SY Ha, D Lee, K Sankar, EK Koltsova… - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) has one of the highest mortality rates among solid cancers.
Late diagnosis and a lack of efficacious treatment options contribute to the dismal prognosis …
Late diagnosis and a lack of efficacious treatment options contribute to the dismal prognosis …
Immunotherapy Monitoring with Immune Checkpoint Inhibitors Based on [18F]FDG PET/CT in Metastatic Melanomas and Lung Cancer
E Lopci - Journal of Clinical Medicine, 2021 - mdpi.com
Immunotherapy with checkpoint inhibitors has prompted a major change not only in cancer
treatment but also in medical imaging. In parallel with the implementation of new drugs …
treatment but also in medical imaging. In parallel with the implementation of new drugs …
PET/CT molecular imaging in the era of immune-checkpoint inhibitors therapy
Y Gao, C Wu, X Chen, L Ma, X Zhang, J Chen… - Frontiers in …, 2022 - frontiersin.org
Cancer immunotherapy, especially immune-checkpoint inhibitors (ICIs), has paved a new
way for the treatment of many types of malignancies, particularly advanced-stage cancers …
way for the treatment of many types of malignancies, particularly advanced-stage cancers …
Prognostic value of 18F-FDG PET/CT in patients with advanced or metastatic non-small-cell lung cancer treated with immune checkpoint inhibitors: A systematic …
T Ling, L Zhang, R Peng, C Yue, L Huang - Frontiers in Immunology, 2022 - frontiersin.org
Purpose This study aimed to investigate the value of 18F-fluorodeoxyglucose positron
emission tomography/computed tomography (18F-FDG PET/CT) in predicting early …
emission tomography/computed tomography (18F-FDG PET/CT) in predicting early …