Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity

TN Kakuda - Clinical therapeutics, 2000 - Elsevier
OBJECTIVE: This paper reviews the function of the mitochondria and the mechanisms by
which nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs) cause …

HIV chemotherapy

DD Richman - Nature, 2001 - nature.com
The use of chemotherapy to suppress replication of the human immunodeficiency virus (HIV)
has transformed the face of AIDS in the developed world. Pronounced reductions in illness …

Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2016 recommendations of the International Antiviral Society–USA panel

HF Günthard, MS Saag, CA Benson, C Del Rio, JJ Eron… - Jama, 2016 - jamanetwork.com
Importance New data and therapeutic options warrant updated recommendations for the use
of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. Objective To …

[HTML][HTML] Sexually transmitted diseases treatment guidelines, 2015

KA Workowski, GA Bolan… - 2015 - cdc.gov
These guidelines for the treatment of persons who have or are at risk for sexually transmitted
diseases (STDs) were updated by CDC after consultation with a group of professionals …

Cardiovascular disease risk factors in HIV patients–association with antiretroviral therapy. Results from the DAD study

N Friis-Møller, R Weber, P Reiss, R Thiébaut, O Kirk… - Aids, 2003 - journals.lww.com
Objective: To determine the prevalence of risk factors for cardiovascular disease (CVD)
among HIV-infected persons, and to investigate any association between such risk factors …

Medication adherence in HIV-infected adults: effect of patient age, cognitive status, and substance abuse

CH Hinkin, DJ Hardy, KI Mason, SA Castellon… - Aids, 2004 - journals.lww.com
Objective: To examine the predictors of antiretroviral adherence among HIV-infected adults,
with a particular focus on advancing age, neuropsychological dysfunction, and substance …

Antiretroviral-drug resistance among patients recently infected with HIV

SJ Little, S Holte, JP Routy, ES Daar… - … England Journal of …, 2002 - Mass Medical Soc
Background Among persons in North America who are newly infected with the human
immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs …

Validation of a simplified medication adherence questionnaire in a large cohort of HIV-infected patients: the GEEMA Study

H Knobel, J Alonso, JL Casado, J Collazos, J González… - Aids, 2002 - journals.lww.com
Objective To assess the effectiveness of the simplified medication adherence questionnaire
(SMAQ) in identifying non-adherent patients. Design Prospective observational study of …

Rates of disease progression by baseline CD4 cell count and viral load after initiating triple-drug therapy

RS Hogg, B Yip, KJ Chan, E Wood, KJP Craib… - Jama, 2001 - jamanetwork.com
ContextCurrent recommendations for initiation of antiretroviral therapy in patients infected
with human immunodeficiency virus type 1 (HIV) are based on CD4 T-lymphocyte cell …

Adherence to treatment in adolescents

D Taddeo, M Egedy, JY Frappier - Paediatrics & child health, 2008 - academic.oup.com
Health care professionals must be alert to the high prevalence of low adherence to treatment
during adolescence. Low adherence increases morbidity and medical complications …