Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity
TN Kakuda - Clinical therapeutics, 2000 - Elsevier
OBJECTIVE: This paper reviews the function of the mitochondria and the mechanisms by
which nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs) cause …
which nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs) cause …
HIV chemotherapy
DD Richman - Nature, 2001 - nature.com
The use of chemotherapy to suppress replication of the human immunodeficiency virus (HIV)
has transformed the face of AIDS in the developed world. Pronounced reductions in illness …
has transformed the face of AIDS in the developed world. Pronounced reductions in illness …
Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2016 recommendations of the International Antiviral Society–USA panel
Importance New data and therapeutic options warrant updated recommendations for the use
of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. Objective To …
of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. Objective To …
[HTML][HTML] Sexually transmitted diseases treatment guidelines, 2015
KA Workowski, GA Bolan… - 2015 - cdc.gov
These guidelines for the treatment of persons who have or are at risk for sexually transmitted
diseases (STDs) were updated by CDC after consultation with a group of professionals …
diseases (STDs) were updated by CDC after consultation with a group of professionals …
Cardiovascular disease risk factors in HIV patients–association with antiretroviral therapy. Results from the DAD study
N Friis-Møller, R Weber, P Reiss, R Thiébaut, O Kirk… - Aids, 2003 - journals.lww.com
Objective: To determine the prevalence of risk factors for cardiovascular disease (CVD)
among HIV-infected persons, and to investigate any association between such risk factors …
among HIV-infected persons, and to investigate any association between such risk factors …
Medication adherence in HIV-infected adults: effect of patient age, cognitive status, and substance abuse
CH Hinkin, DJ Hardy, KI Mason, SA Castellon… - Aids, 2004 - journals.lww.com
Objective: To examine the predictors of antiretroviral adherence among HIV-infected adults,
with a particular focus on advancing age, neuropsychological dysfunction, and substance …
with a particular focus on advancing age, neuropsychological dysfunction, and substance …
Antiretroviral-drug resistance among patients recently infected with HIV
Background Among persons in North America who are newly infected with the human
immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs …
immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs …
Validation of a simplified medication adherence questionnaire in a large cohort of HIV-infected patients: the GEEMA Study
H Knobel, J Alonso, JL Casado, J Collazos, J González… - Aids, 2002 - journals.lww.com
Objective To assess the effectiveness of the simplified medication adherence questionnaire
(SMAQ) in identifying non-adherent patients. Design Prospective observational study of …
(SMAQ) in identifying non-adherent patients. Design Prospective observational study of …
Rates of disease progression by baseline CD4 cell count and viral load after initiating triple-drug therapy
ContextCurrent recommendations for initiation of antiretroviral therapy in patients infected
with human immunodeficiency virus type 1 (HIV) are based on CD4 T-lymphocyte cell …
with human immunodeficiency virus type 1 (HIV) are based on CD4 T-lymphocyte cell …
Adherence to treatment in adolescents
D Taddeo, M Egedy, JY Frappier - Paediatrics & child health, 2008 - academic.oup.com
Health care professionals must be alert to the high prevalence of low adherence to treatment
during adolescence. Low adherence increases morbidity and medical complications …
during adolescence. Low adherence increases morbidity and medical complications …