Isothermal titration calorimetry (ITC) is a technique for evaluating the thermodynamic profiles
of connection between two molecules, allowing the experimental design of nanoparticles …

Mutations are changes in the nucleotide sequence that derive from external factors or errors
during cell division. They are the source of many diseases such as cancers, sickle cell …

Plasmonic nanopores combined with Raman spectroscopy are emerging as platforms for
single-molecule detection and sequencing in label-free mode. Recently, the ability of …

Traditional immunoassay methods often face challenges due to the labeling procedure of
protein enzymes, the use of multiple antibodies, and severe conditions. To address these …

Understanding the patterns of noncovalent adsorption of double-stranded nucleic acids
(dsDNA) on gold nanoparticles (GNPs) was the aim of this study. It was found that the high …

The rapid growth of in vitro nucleic acid replication has offered a powerful tool for clinical
diagnosis, food safety detection and environmental monitorning. Successful implementation …

Deoxyribonucleic acid (DNA) represents the main reservoir of genetic information in the
cells, which is why it is protected in the nucleus. Entry into the nucleus is, in general, difficult …

In this work, we proposed a sensitive and selective colorimetric assay for single nucleotide
mutation (SNM) detection combining rolling circle amplification (RCA) and G …

A colorimetric assay for human papillomavirus (HPV) DNA was developed based on the
retardation of the avidin-induced aggregation of gold nanoparticles (AuNPs) by HPV DNA …

Endogenous cell metabolism and chemical reactions can induce oxidative DNA damage,
which is involved in the development of different diseases. In this work, a label-free …