Metabolic engineering is the directed improvement of cellular properties through the
modification of specific biochemical reactions or the introduction of new ones, with the use of …

As the details of the chemical transformations in metabolism have become increasingly
clear, and the enzymes catalysing many of the reactions have been characterized, it is …

Abstract Flux Balance Analysis (FBA) has been used in the past to analyze microbial
metabolic networks. Typically, FBA is used to study the metabolic flux at a particular steady …

There is little doubt that the central areas of traditional biochemistry (such as metabolism,
metabolic regulation and enzymology) are currently unfashionable and generally regarded …

There is no doubt that nowadays, biology benefits greatly from mathematics. In particular,
cellular biology is, besides population dynamics, a field where tech niques of mathematical …

Metabolic engineering emerged 20 years ago as the discipline occupied with the directed
modification of metabolic pathways for the microbial synthesis of various products. As such …

An enormous variety of nonlinear differential equations and functions have been recast
exactly in the canonical form called an S-system. This is a system of nonlinear ordinary …

Biochemical systems theory (BST) is the foundation for a set of analytical andmodeling tools
that facilitate the analysis of dynamic biological systems. This paper depicts major …

A First Course in Systems Biology is an introduction for advanced undergraduate and
graduate students to the growing field of systems biology. Its main focus is the development …

Measurements of rates of glucose uptake and of glycerol and ethanol formation combined
with knowledge of the metabolic pathways involved in S. cerevisiae were employed to …