The alphaviruses are a genus of 26 enveloped viruses that cause disease in humans and
domestic animals. Mosquitoes or other hematophagous arthropods serve as vectors for …

The effect of reduced temperature on synchronized transport of SFV membrane proteins
from the ER via the Golgi complex to the surface of BHK-21 cells revealed two membrane …

Alphaviruses are enveloped positive sense RNA viruses and include serious human
pathogens, such as the encephalitic alphaviruses and Chikungunya virus. Alphaviruses are …

In the last few years, our knowledge of the molecular biology of viruses has been greatly
expanded by the technology of nucleic acid sequencing. Determination of the complete …

Semliki Forest virus (SFV) particles are released from infected cells by budding of
nucleocapsids through plasma membrane regions that are modified by virus spike proteins …

We recently described a system for heterologous gene expression in a variety of mammalian
cell types that is based on an efficiently replicating Semliki Forest virus (SFV) variant in …

For 30 years it was thought the alphavirus 6K gene encoded a single 6 kDa protein.
However, through a bioinformatics search 10 years ago, it was discovered that there is a …

Alphaviruses are small highly ordered enveloped RNA viruses, which replicate very
efficiently in the infected cell. They consist of a nucleocapsid (NC) and a surrounding …

Our knowledge of the molecular biology of virus replication has expanded dramatically in
the last few years, especially with the advent of rapid techniques for obtaining the nucleotide …

So far it has been demonstrated that the signal sequence of proteins which are made at the
ER functions both at the level of protein targeting to the ER and in initiation of chain …