Pathophysiology of diabetic dyslipidaemia: where are we?

B Vergès - Diabetologia, 2015 - Springer
Cardiovascular disease is a major cause of morbidity and mortality in patients with type 2
diabetes mellitus, with a two-to fourfold increase in cardiovascular disease risk compared …

New insights into the pathophysiology of dyslipidemia in type 2 diabetes

MR Taskinen, J Borén - Atherosclerosis, 2015 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality for
patients with type 2 diabetes, despite recent significant advances in management strategies …

Obesity, adiposity, and dyslipidemia: a consensus statement from the National Lipid Association

HE Bays, PP Toth, PM Kris-Etherton, N Abate… - Journal of clinical …, 2013 - Elsevier
The term “fat” may refer to lipids as well as the cells and tissue that store lipid (ie, adipocytes
and adipose tissue).“Lipid” is derived from “lipos,” which refers to animal fat or vegetable oil …

Mechanisms linking obesity with cardiovascular disease

LF Van Gaal, IL Mertens, CE De Block - Nature, 2006 - nature.com
Obesity increases the risk of cardiovascular disease and premature death. Adipose tissue
releases a large number of bioactive mediators that influence not only body weight …

Overproduction of very low–density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome

M Adiels, SO Olofsson, MR Taskinen… - … , and vascular biology, 2008 - Am Heart Assoc
Insulin resistance is a key feature of the metabolic syndrome and often progresses to type 2
diabetes. Both insulin resistance and type 2 diabetes are characterized by dyslipidemia …

[HTML][HTML] Obesity and dyslipidemia

KR Feingold - 2015 - europepmc.org
Abnormalities in lipid metabolism are very commonly observed in patients who are obese.
Approximately 60-70% of patients with obesity are dyslipidemic. The lipid abnormalities in …

Apolipoprotein B and apolipoprotein A‐I: risk indicators of coronary heart disease and targets for lipid‐modifying therapy

G Walldius, I Jungner - Journal of internal medicine, 2004 - Wiley Online Library
Although LDL cholesterol (LDL‐C) is associated with an increased risk of coronary heart
disease, other lipoproteins and their constituents, apolipoproteins, may play an important …

Hypertriglyceridemia secondary to obesity and diabetes

S Subramanian, A Chait - Biochimica et Biophysica Acta (BBA)-Molecular …, 2012 - Elsevier
Hypertriglyceridemia is a common lipid abnormality in persons with visceral obesity,
metabolic syndrome and type 2 diabetes. Hypertriglyceridemia typically occurs in …

Apolipoprotein C-III: understanding an emerging cardiovascular risk factor

EMM Ooi, PHR Barrett, DC Chan, GF Watts - Clinical science, 2008 - portlandpress.com
The concurrence of visceral obesity, insulin resistance and dyslipidaemia comprises the
concept of the metabolic syndrome. The metabolic syndrome is an escalating problem in …

Postprandial hypertriglyceridemia as a coronary risk factor

J Borén, N Matikainen, M Adiels, MR Taskinen - Clinica chimica acta, 2014 - Elsevier
Postprandial hypertriglyceridemia is now established as an important risk factor for
cardiovascular disease (CVD). This metabolic abnormality is principally initiated by …