Streptococcus mitis: walking the line between commensalism and pathogenesis

J Mitchell - Molecular oral microbiology, 2011 - Wiley Online Library
Streptococcus mitis is a viridans streptococcus and a normal commensal of the human
oropharynx. However, S. mitis can escape from this niche and cause a variety of infectious …

The cholesterol-dependent cytolysin family of gram-positive bacterial toxins

AP Heuck, PC Moe, BB Johnson - … proteins: structure and function in health …, 2010 - Springer
The cholesterol-dependent cytolysins (CDCs) are a family of β-barrel pore-forming toxins
secreted by Gram-positive bacteria. These toxins are produced as water-soluble monomeric …

Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients

J Chhibber-Goel, V Singhal, D Bhowmik… - NPJ biofilms and …, 2016 - nature.com
Coronary artery disease is an inflammatory disorder characterized by narrowing of coronary
arteries due to atherosclerotic plaque formation. To date, the accumulated epidemiological …

Curcumin-loaded polysaccharide nanoparticles: Optimization and anticariogenic activity against Streptococcus mutans

A Maghsoudi, F Yazdian, S Shahmoradi… - Materials Science and …, 2017 - Elsevier
Curcumin was loaded into different polysaccharide nanoparticles chitosan, alginate and
starch, using the desolvation method. Curcumin-loaded nanoparticles exhibited enhanced …

Curcumin-loaded chitosan/carboxymethyl starch/montmorillonite bio-nanocomposite for reduction of dental bacterial biofilm formation

S Jahanizadeh, F Yazdian, A Marjani, M Omidi… - International journal of …, 2017 - Elsevier
A novel bio nanocomposite of Carboxymethyl Starch (CMS)-Chitosan (CS)-Montmorillonite
(MMT) was developed for Curcumin delivery. To improve Curcumin entrapment into Cs-CMS …

The Genome of Streptococcus mitis B6 - What Is a Commensal?

D Denapaite, R Brückner, M Nuhn, P Reichmann… - PloS one, 2010 - journals.plos.org
Streptococcus mitis is the closest relative of the major human pathogen S. pneumoniae. The
2, 15 Mb sequence of the Streptococcus mitis B6 chromosome, an unusually high-level beta …

Detection of large numbers of pneumococcal virulence genes in streptococci of the mitis group

C Johnston, J Hinds, A Smith… - Journal of clinical …, 2010 - Am Soc Microbiol
Seven streptococcal isolates from the mitis group were analyzed for the presence of
pneumococcal gene homologues by comparative genomic hybridization studies with …

Presence of Nonhemolytic Pneumolysin in Serotypes of Streptococcus pneumoniae Associated with Disease Outbreaks

JMC Jefferies, CHG Johnston… - Journal of Infectious …, 2007 - academic.oup.com
Pneumolysin is an important virulence factor of the human pathogen Streptococcus
pneumoniae. Sequence analysis of the ply gene from 121 clinical isolates of S. pneumoniae …

Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation

MA Bewley, M Naughton, J Preston, A Mitchell… - MBio, 2014 - Am Soc Microbiol
Intracellular killing of Streptococcus pneumoniae is complemented by induction of
macrophage apoptosis. Here, we show that the toxin pneumolysin (PLY) contributes both to …

Streptococcus mitis as a New Emerging Pathogen in Pediatric Age: Case Report and Systematic Review

C Colomba, V Garbo, G Boncori, C Albano, S Bagarello… - Antibiotics, 2023 - mdpi.com
Streptococcus mitis, a normal inhabitant of the oral cavity, is a member of Viridans Group
Streptococci (VGS). Generally recognized as a causative agent of invasive diseases in …