Gonorrhoea is a major public health concern globally. Increasing incidence and sporadic
ceftriaxone-resistant cases, including treatment failures, are growing concerns. The 2020 …

Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a serious public health problem,
compromising the management and control of gonorrhoea globally. Resistance in N …

Background Genomic surveillance using quality-assured whole-genome sequencing (WGS)
together with epidemiological and antimicrobial resistance (AMR) data is essential to …

Changes since 2011 guideline• First line empirical treatment is now monotherapy with
ceftriaxone 1 g intramuscularly• If antimicrobial susceptibility test results from all sites of …

Background Traditional methods for molecular epidemiology of Neisseria gonorrhoeae are
suboptimal. Whole-genome sequencing (WGS) offers ideal resolution to describe population …

Historically, epidemiological investigation and surveillance for bacterial antimicrobial
resistance (AMR) has relied on low-resolution isolate-based phenotypic analyses …

Background In this phase 2 study, we evaluated the efficacy and safety of oral gepotidacin, a
novel triazaacenaphthylene bacterial type II topoisomerase inhibitor, for the treatment of …

Neisseria gonorrhoeae is an etiologic agent of gonorrhoea, one of the most common
sexually transmitted diseases caused by bacteria. For many years, infections caused by N …

We describe a multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone
resistance and azithromycin intermediate resistance in a heterosexual man in Denmark …

Worldwide, the incidence of bacterial sexually transmitted infections (STIs) has shown a
significant increase in recent years. In Germany, this circumstance is reflected by a rise in …