The human tissue kallikrein gene family was, until recently, thought to consist of only three
genes. Two of these human kallikreins, prostate-specific antigen and human glandular …

Human tissue kallikreins (hKs), which are encoded by the largest contiguous cluster of
protease genes in the human genome, are secreted serine proteases with diverse …

The 15 members of the kallikrein-related serine peptidase (KLK) family have diverse tissue-
specific expression profiles and putative proteolytic functions. The kallikrein family is also …

Tissue kallikreins are members of the S1 family (clan SA) of trypsin-like serine proteases
and are present in at least six mammalian orders. In humans, tissue kallikreins (hK) are …

Background: Screening biomarkers for ovarian cancer are needed because of its late stage
at diagnosis and poor survival. We used microarray technology to identify overexpressed …

Kallikreins are a subgroup of the serine protease enzyme family. Until recently, it was
thought that the human kallikrein gene family contained only three members. In the past 3 …

The traditional human kallikrein gene family consists of three genes, namely KLK1
[encoding human kallikrein 1 (hK1) or pancreatic/renal kallikrein], KLK2 (encoding hK2 …

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective
biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family …

We report the characterization of a novel serine protease of the chymotrypsin family, recently
isolated by cDNA-representational difference analysis, as a gene overexpressed in …

The identification of genes with selective expression in specific organs or cell types provides
an entry point for understanding biological processes that occur uniquely within a particular …