Expansion microscopy of apicomplexan parasites

B Liffner, S Absalon - Molecular Microbiology, 2024 - Wiley Online Library
Apicomplexan parasites comprise significant pathogens of humans, livestock and wildlife,
but also represent a diverse group of eukaryotes with interesting and unique cell biology …

Cytoskeleton organization in formation and motility of apicomplexan parasites

RG Douglas, RW Moon… - Annual Review of …, 2024 - annualreviews.org
Apicomplexan parasites are a group of eukaryotic protozoans with diverse biology that have
affected human health like no other group of parasites. These obligate intracellular parasites …

Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy

B Liffner, AKC Diaz, J Blauwkamp, D Anaguano… - Elife, 2023 - elifesciences.org
Apicomplexan parasites exhibit tremendous diversity in much of their fundamental cell
biology, but study of these organisms using light microscopy is often hindered by their small …

Putative prefoldin complex subunit 5 of Plasmodium berghei is crucial for microtubule formation and parasite development in the mosquito

R Beyeler, M Jordan, L Dorner, B He… - Molecular …, 2024 - Wiley Online Library
Plasmodium sporozoite development in and egress from oocysts in the Anopheles mosquito
remains largely enigmatic. In a previously performed high‐throughput knockout screen, the …

Characterization of the extracellular vesicles, ultrastructural morphology, and intercellular interactions of multiple clinical isolates of the brain-eating amoeba …

AC Russell, P Bush, G Grigorean, DE Kyle - Frontiers in Microbiology, 2023 - frontiersin.org
Introduction As global temperatures rise to unprecedented historic levels, so too do the
latitudes of habitable niches for the pathogenic free-living amoeba, Naegleria fowleri. This …

A subpellicular microtubule dynein transport machinery regulates ookinete morphogenesis for mosquito transmission of Plasmodium yoelii

B Liu, C Liu, Z Li, W Liu, H Cui, J Yuan - Nature Communications, 2024 - nature.com
The cortical cytoskeleton of subpellicular microtubules (SPMTs) supports the Plasmodium
ookinete morphogenesis during mosquito transmission of malaria. SPMTs are hypothesized …

Architecture of the Toxoplasma gondii apical polar ring and its role in gliding motility and invasion

B Ren, R Haase, S Patray, Q Nguyen, B Maco… - Proceedings of the …, 2024 - pnas.org
In Toxoplasma gondii, the conoid comprises a cone with spiraling tubulin fibers, preconoidal
rings, and intraconoidal microtubules. This dynamic organelle undergoes extension and …

The initiation and early development of the tubulin-containing cytoskeleton in the human parasite Toxoplasma gondii

LFA Padilla, JM Murray, K Hu - Molecular biology of the cell, 2024 - Am Soc Cell Biol
The tubulin-containing cytoskeleton of the human parasite Toxoplasma gondii includes
several distinct structures: the conoid, formed of 14 ribbon-like tubulin polymers, and the …

The initiation and early development of the tubulin-containing cytoskeleton in the human parasite Toxoplasma gondii

LF Arias Padilla, JM Murray, K Hu - bioRxiv, 2023 - biorxiv.org
The tubulin-containing cytoskeleton of the human parasite Toxoplasma gondii includes
several distinct structures: the conoid, formed of 14 ribbon-like tubulin polymers, and the …

Glycosylation, Trafficking, and Structural Studies in the Sporozoite Stage of the Malaria Parasite

S Patray - 2023 - jscholarship.library.jhu.edu
Malaria remains a major public health problem around the world, with an estimated death
toll of 619 000 in 2021. Malaria is caused by the Apicomplexa parasite Plasmodium, which …