Nucleotide-binding oligomerization domain (NBD), leucine-rich repeat (LRR) containing
protein family (NLRs) are intracellular pattern recognition receptors that mediate innate …

Among the few non-structural proteins encoded by the picornaviral genome, the 2A protein
is particularly special, irrespective of structure or function. During the evolution of the …

The emergence of new and resistant viruses is a serious global burden. Conventional
antiviral therapy with small molecules has led to the development of resistant mutants. In the …

Background: Group B enteroviruses are common causes of acute myocarditis, which can be
a precursor of chronic myocarditis and dilated cardiomyopathy, leading causes of heart …

The interaction of rice glutelin (RG) with amylose was characterized by spectroscopic and
molecular docking studies. The intrinsic fluorescence of RG increased upon the addition of …

Abstract Background The Biochemical Algorithms Library (BALL) is a comprehensive rapid
application development framework for structural bioinformatics. It provides an extensive …

Duck hepatitis A virus type 1,(DHAV-1) 2A2 pro, is one of the most highly conserved viral
proteins within the DHAV serotypes. However, its effect on host cells is unclear. We …

Calpain is a family of neutral cysteine proteinase involved in many physiological and
pathological processes including virus replication, autophagy and apoptosis. Previous study …

One strategy to counter viruses that persistently cause outbreaks is to design molecules that
can specifically inhibit an essential multifunctional viral protease. Herein, we present such a …

Hand, foot, and mouth disease (HFMD) is a contagious disease in toddlers and youth,
mainly caused by Coxsackievirus-A16 (CA16) infection. On the other hand, liquid smoke …