[HTML][HTML] Machine learning in amyotrophic lateral sclerosis: achievements, pitfalls, and future directions
V Grollemund, PF Pradat, G Querin, F Delbot… - Frontiers in …, 2019 - frontiersin.org
Background: Amyotrophic Lateral Sclerosis (ALS) is a relentlessly progressive
neurodegenerative condition with limited therapeutic options at present. Survival from …
neurodegenerative condition with limited therapeutic options at present. Survival from …
[HTML][HTML] Clinical and radiological markers of extra-motor deficits in amyotrophic lateral sclerosis
F Christidi, E Karavasilis, M Rentzos, N Kelekis… - Frontiers in …, 2018 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is now universally recognized as a complex multisystem
disorder with considerable extra-motor involvement. The neuropsychological manifestations …
disorder with considerable extra-motor involvement. The neuropsychological manifestations …
Patterned functional network disruption in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease primarily
affecting motor function, with additional evidence of extensive nonmotor involvement …
affecting motor function, with additional evidence of extensive nonmotor involvement …
[HTML][HTML] Pathological neural networks and artificial neural networks in ALS: diagnostic classification based on pathognomonic neuroimaging features
P Bede, A Murad, O Hardiman - Journal of neurology, 2021 - Springer
The description of group-level, genotype-and phenotype-associated imaging traits is
academically important, but the practical demands of clinical neurology centre on the …
academically important, but the practical demands of clinical neurology centre on the …
Hippocampal pathology in amyotrophic lateral sclerosis: selective vulnerability of subfields and their associated projections
F Christidi, E Karavasilis, M Rentzos, G Velonakis… - Neurobiology of …, 2019 - Elsevier
Although hippocampal involvement in amyotrophic lateral sclerosis (ALS) has been
consistently highlighted by postmortem studies, memory impairment remains under …
consistently highlighted by postmortem studies, memory impairment remains under …
Primary lateral sclerosis: a distinct entity or part of the ALS spectrum?
E Finegan, RH Chipika, SLH Shing… - … Lateral Sclerosis and …, 2019 - Taylor & Francis
Primary lateral sclerosis (PLS) has been traditionally viewed as a distinct upper motor
neuron condition (UMN) but is increasingly regarded as a sub-phenotype within the …
neuron condition (UMN) but is increasingly regarded as a sub-phenotype within the …
[HTML][HTML] Tracking a fast-moving disease: longitudinal markers, monitoring, and clinical trial endpoints in ALS
RH Chipika, E Finegan, S Li Hi Shing… - Frontiers in …, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) encompasses a heterogeneous group of phenotypes
with different progression rates, varying degree of extra-motor involvement and divergent …
with different progression rates, varying degree of extra-motor involvement and divergent …
Neural correlates of motor imagery of gait in amyotrophic lateral sclerosis
M Abidi, G De Marco, F Grami, N Termoz… - Journal of Magnetic …, 2021 - Wiley Online Library
Background Gait impairment is poorly characterized in amyotrophic lateral sclerosis (ALS),
despite increasing evidence of extrapyramidal and cerebellar dysfunction. Gait impairment …
despite increasing evidence of extrapyramidal and cerebellar dysfunction. Gait impairment …
[HTML][HTML] Spinal cord imaging in amyotrophic lateral sclerosis: historical concepts—novel techniques
MM El Mendili, G Querin, P Bede, PF Pradat - Frontiers in neurology, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease
with no effective disease modifying therapies at present. Spinal cord degeneration is a …
with no effective disease modifying therapies at present. Spinal cord degeneration is a …
[HTML][HTML] Clusters of anatomical disease-burden patterns in ALS: a data-driven approach confirms radiological subtypes
P Bede, A Murad, J Lope, O Hardiman, KM Chang - Journal of neurology, 2022 - Springer
Amyotrophic lateral sclerosis (ALS) is associated with considerable clinical heterogeneity
spanning from diverse disability profiles, differences in UMN/LMN involvement, divergent …
spanning from diverse disability profiles, differences in UMN/LMN involvement, divergent …