Tissue engineering and regenerative medicine involve many different artificial and biologic
materials, frequently integrated in composite scaffolds, which can be repopulated with …

Organ transplantation is an effective treatment for chronic organ dysfunctioning conditions.
However, a dearth of available donor organs for transplantation leads to the death of …

Decades of research have been undertaken towards the goal of tissue engineering using
xenogeneic scaffolds. The primary advantages associated with use of xenogeneic tissue …

Decellularized tissues have become a common regenerative medicine platform with multiple
materials being researched in academic laboratories, tested in animal studies, and used …

Decellularized xenogenic or allogenic heart valves have been used as starter matrix for
tissue-engineering of valve replacements with (pre-) clinical promising results. However …

The tissue-engineered heart valve portends a new era in the field of valve replacement.
Decellularized heart valves are of great interest as a scaffold for the tissue-engineered heart …

Decellularized scaffolds are promising clinically translational biomaterials that can be
applied to direct cell responses and promote tissue regeneration. Bioscaffolds derived from …

Tissue-engineered heart valves (TEHV) have been proposed as a promising solution for the
clinical needs of pediatric patients. In vivo studies have shown TEHV leaflet contraction and …

Heart valve replacement is often the only solution for patients suffering from valvular heart
disease. However, currently available valve replacements require either life‐long …

Designing a successful biological interface for a biomaterial requires the application of
concepts from multiple fields, including materials science, surface science, nanoscience …