Iron overload disorders: Growth and gonadal dysfunction in childhood and adolescence

M Tenuta, B Cangiano, G Rastrelli… - Pediatric Blood & …, 2024 - Wiley Online Library
Hemochromatosis (HC) is characterized by the progressive accumulation of iron in the body,
resulting in organ damage. Endocrine complications are particularly common, especially …

Prevalence of Hypogonadism in β-Thalassemia major patients from gaza strip

A Hamed, M Zughbur, E Shaheen - Jordan Journal of …, 2021 - archives.ju.edu.jo
This study was conducted to determine the prevalence of hypogonadism among β-
Thalassemia Major (β-TM) adolescent patients, and the role of iron chelation therapy (ICT) in …

Association of GDF15 levels with body mass index and endocrine status in β‐thalassaemia

Y Karusheva, CJ Petry, N Yasara… - Clinical …, 2023 - Wiley Online Library
Objective GDF15 has emerged as a stress‐induced hormone, acting on the brain to reduce
food intake and body weight while affecting neuroendocrine function. Very high GDF15 …

Evaluation of Reproductive Hormones in Patients with β-Thalassemia Major in Misan Province, Iraq.

TNAL AL-Zuhairy, ZAJR AL-Ali - Medico-Legal Update, 2020 - search.ebscohost.com
Assessment of serum ferritin, FSH, LH, estradiol, testosterone levels in β-thalassemia major
patients. A total 50 (30 male and 20 female) children with β-thalassemia major patients with …

Endocrine dysfunction in transfusion dependent thalassemia patients from central India

R Saras, A Bharani, GS Eske, N Jain - Asian Journal of Medical …, 2023 - ajmsjournal.info
Background: Thalassemia refers to a group of genetically inherited diseases characterized
by decreased or absent synthesis of normal globin chains resulting in defective globin …

Investigation and Management of Endocrinopathies in Thalassaemia Major

K Al-Hourani, JLS Hua, P De - Human Blood Group Systems and …, 2021 - books.google.com
A combination of sub-therapeutic chelation and subsequent iron overload are regarded as
the principal drivers of endocrine dysfunction in thalassaemia. The clinical presentation of …

Magnetic Resonance Imaging Versus Serum Iron Status as Diagnostic Tools for Pituitary Iron Overload in Children with Beta Thalassemia

AA Hagag, RA El-Shafey… - … of Advances in …, 2021 - science.classicopenlibrary.com
Background: Thalassemia is a common genetic disorder associated with endocrine
disorders. Iron deposition may start in the anterior pituitary gland, but clinical signs are …