Recent insights of T cell receptor-mediated signaling pathways for T cell activation and development
JR Hwang, Y Byeon, D Kim, SG Park - Experimental & molecular …, 2020 - nature.com
T cell activation requires extracellular stimulatory signals that are mainly mediated by T cell
receptor (TCR) complexes. The TCR recognizes antigens on major histocompatibility …
receptor (TCR) complexes. The TCR recognizes antigens on major histocompatibility …
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis
N Beauchemin, A Arabzadeh - Cancer and Metastasis Reviews, 2013 - Springer
The discovery of the carcinoembryonic antigen (CEA) as a tumor marker for colorectal
cancer some 50 years ago became the first step in the identification of a much larger family …
cancer some 50 years ago became the first step in the identification of a much larger family …
CEACAM1: contact-dependent control of immunity
SD Gray-Owen, RS Blumberg - Nature Reviews Immunology, 2006 - nature.com
The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins
has been implicated in various intercellular-adhesion and intracellular-signalling-mediated …
has been implicated in various intercellular-adhesion and intracellular-signalling-mediated …
The junctional epithelium: from health to disease
DD Bosshardt, NP Lang - Journal of dental research, 2005 - journals.sagepub.com
The junctional epithelium is located at a strategically important interface between the
gingival sulcus, populated with bacteria, and the periodontal soft and mineralized …
gingival sulcus, populated with bacteria, and the periodontal soft and mineralized …
Pathogenesis of Afa/Dr Diffusely Adhering Escherichia coli
AL Servin - Clinical microbiology reviews, 2005 - Am Soc Microbiol
Over the last few years, dramatic increases in our knowledge about diffusely adhering
Escherichia coli (DAEC) pathogenesis have taken place. The typical class of DAEC includes …
Escherichia coli (DAEC) pathogenesis have taken place. The typical class of DAEC includes …
Neisserial binding to CEACAM1 arrests the activation and proliferation of CD4+ T lymphocytes
IC Boulton, SD Gray-Owen - Nature immunology, 2002 - nature.com
Infection with Neisseria gonorrhoeae can trigger an intense inflammatory response, yet
there is little specific immune response or development of immune memory. In addition …
there is little specific immune response or development of immune memory. In addition …
CEACAM1 as a multi-purpose target for cancer immunotherapy
ABSTRACT CEACAM1 is an extensively studied cell surface molecule with established
functions in multiple cancer types, as well as in various compartments of the immune system …
functions in multiple cancer types, as well as in various compartments of the immune system …
CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease
A Thies, I Moll, J Berger, C Wagener… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: The cell adhesion molecule CEACAM1 is involved in intercellular adhesion and
subsequent signal transduction events in a number of epithelia. CEACAM1 downregulation …
subsequent signal transduction events in a number of epithelia. CEACAM1 downregulation …
CEACAM1 structure and function in immunity and its therapeutic implications
The type I membrane protein receptor carcinoembryonic antigen-related cell adhesion
molecule 1 (CEACAM1) distinctively exhibits significant alternative splicing that allows for …
molecule 1 (CEACAM1) distinctively exhibits significant alternative splicing that allows for …
CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity
NK cells are able to kill virus-infected and tumor cells via a panel of lysis receptors. Cells
expressing class I MHC proteins are protected from lysis primarily due to the interactions of …
expressing class I MHC proteins are protected from lysis primarily due to the interactions of …