Hypogonadism and cryptorchidism

W Rodprasert, HE Virtanen, JA Mäkelä… - Frontiers in …, 2020 - frontiersin.org
Congenital cryptorchidism (undescended testis) is one of the most common congenital
urogenital malformations in boys. Prevalence of cryptorchidism at birth among boys born …

Distinguishing constitutional delay of growth and puberty from isolated hypogonadotropic hypogonadism: critical appraisal of available diagnostic tests

J Harrington, MR Palmert - The Journal of Clinical …, 2012 - academic.oup.com
Context: Determining the etiology of delayed puberty during initial evaluation can be
challenging. Specifically, clinicians often cannot distinguish constitutional delay of growth …

Evaluation and treatment of cryptorchidism: AUA guideline

TF Kolon, CDA Herndon, LA Baker, LS Baskin… - The Journal of …, 2014 - auajournals.org
Purpose: Cryptorchidism is one of the most common pediatric disorders of the male
endocrine glands and the most common genital disorder identified at birth. This guideline is …

Role of radical oxygen species in rat testicular germ cell apoptosis induced by heat stress

M Ikeda, H Kodama, J Fukuda, Y Shimizu… - Biology of …, 1999 - academic.oup.com
The present study was designed to clarify the role of radical oxygen species in testicular
germ cell apoptosis induced by heat stress. Testicular cells isolated from immature rats were …

Germ cell apoptosis after treatment of cryptorchidism with human chorionic gonadotropin is associated with impaired reproductive function in the adult.

L Dunkel, S Taskinen, O Hovatta… - The Journal of …, 1997 - Am Soc Clin Investig
Cryptorchidism results in impaired fertility. Reduced numbers of testicular germ cells can be
shown histologically during the first years of life. The process causing germ cell loss in …

Undescended testes: a consensus on management

EM Ritzén - European journal of endocrinology, 2008 - academic.oup.com
The mode of treatment best for undescended testes is controversial, and local traditions
often override knowledge gained from randomized controlled studies. In order to reach a …

Lactate inhibits germ cell apoptosis in the human testis

K Erkkilä, H Aito, K Aalto, V Pentikäinen… - Molecular human …, 2002 - academic.oup.com
Dysregulation of male germ cell apoptosis has been associated with the pathogenesis of
male infertility. Therefore, factors involved in the regulation of germ cell death are being …

Spontaneous germ cell apoptosis in humans: evidence for ethnic differences in the susceptibility of germ cells to programmed cell death

AP Sinha Hikim, C Wang, Y Lue… - The Journal of …, 1998 - academic.oup.com
Spontaneous death of certain classes of germ cells has been shown to be a constant feature
of normal spermatogenesis in a variety of mammalian species, including the human. Recent …

Fas regulates germ cell apoptosis in the human testis in vitro

V Pentikäinen, K Erkkilä… - American Journal of …, 1999 - journals.physiology.org
The Fas-Fas ligand (FasL) system has been implicated in maintaining the immune
privileged nature of the testis. The present report concerns the role of the Fas-FasL system in …

Maldescendus testis

J Toppari, M Kaleva - Hormone Research in Paediatrics, 1999 - karger.com
Maldescendus testis is a common congenital abnormality occurring in 2–5% of full-term
boys at birth in the Western countries. By 3 months of age, the incidence rate spontaneously …