Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

CN Serhan, BD Levy - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: Mechanisms and development

A Yang, Y Wu, G Yu, H Wang - Respiratory Research, 2021 - Springer
Inflammation is an essential mechanism of various diseases. The development and
resolution of inflammation are complex immune-modulation processes which induce the …

Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological …

PC Norris, AC Skulas-Ray, I Riley, CK Richter… - Scientific reports, 2018 - nature.com
Specialized pro-resolving mediator (s)(SPMs) are produced from the endogenous ω-3
polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA) and docosahexaenoic …

Pro-resolving lipid mediators in the pathophysiology of asthma

O Kytikova, T Novgorodtseva, Y Denisenko… - Medicina, 2019 - mdpi.com
Asthma is one of the most important medical and social problems of our time due to the
prevalence and the complexity of its treatment. Chronic inflammation that is characteristic of …

[HTML][HTML] Inflammation and oxidative stress as mediators of the impacts of environmental exposures on human pregnancy: Evidence from oxylipins

BM Welch, EE McNell, ML Edin, KK Ferguson - Pharmacology & …, 2022 - Elsevier
Inflammation and oxidative stress play major roles in healthy and pathological pregnancy.
Environmental exposure to chemical pollutants may adversely affect maternal and fetal …

Exploring the role of LC-PUFA metabolism in pregnancy complications

AA Godhamgaonkar, NS Wadhwani… - … Leukotrienes and Essential …, 2020 - Elsevier
Maternal nutrition during pregnancy plays a significant role in growth and development of
the placenta and influencing pregnancy outcome. Suboptimal nutritional status during early …

Update on oxidative stress and inflammation in pregnant women, unborn children (nasciturus), and newborns–Nutritional and dietary effects

R Domínguez-Perles, A Gil-Izquierdo, F Ferreres… - Free Radical Biology …, 2019 - Elsevier
The scientific background of perinatal pathology, regarding both mother and offspring, from
the lipidomic perspective, has highlighted the possibility of identifying new, promising …

Resolvins lipid mediators: potential therapeutic targets in Alzheimer and Parkinson disease

S Anand, MA Ansari, SK Sukrutha, MN Alomary… - Neuroscience, 2022 - Elsevier
Inflammation and resolution are highly programmed processes involving a plethora of
immune cells. Lipid mediators synthesized from arachidonic acid metabolism play a pivotal …

Fatty acids in normal and pathological pregnancies

AK Mauro, A Rengarajan, C Albright… - Molecular and Cellular …, 2022 - Elsevier
Long chain fatty acids, namely omega-3 and omega-6, are essential fatty acids and are
necessary for proper pregnancy progression and fetal growth and development. Maternal …

Multiassay nutritional metabolomics profiling of low vitamin A status versus adequacy is characterized by reduced plasma lipid mediators among lactating women in …

CM Johnson, R Rosario, A Brito, K Agrawal, R Fanter… - Nutrition Research, 2022 - Elsevier
Low vitamin A (VA) status is common among lactating women in low-income countries.
Lactation has substantial effects on mother's metabolism and VA is required in multiple …