Numerous disease-causing parasites must invade host cells in order to prosper.
Collectively, such pathogens are responsible for a staggering amount of human sickness …

Due to the emergence of multidrug-resistant pathogens, it is necessary to develop options to
fight infections caused by these agents. Lactoferrin (Lf) is a cationic nonheme multifunctional …

Establishment of infection by Trypanosoma cruzi, the agent of Chagas' disease, depends on
a series of events involving interactions of diverse parasite molecules with host components …

Frequent reports on outbreaks of acute Chagas' disease by ingestion of food contaminated
with parasites from triatomine insects illustrate the importance of this mode of transmission …

Paracoccidioides brasiliensis is an important fungal pathogen. The disease it causes,
paracoccidioidomycosis (PCM), ranges from localized pulmonary infection to systemic …

Upon oral infection, Trypanosoma cruzi metacyclic trypomastigotes invade and replicate in
the gastric mucosal epithelium, being apparently uniquely specialized for adhesion to mucin …

Mammalian cell invasion by Trypanosoma cruzi is a complex process in which various
parasite and host cell components interact, triggering the activation of signaling cascades …

Trypanosoma cruzi alternates between different morphological and functional types during
its life cycle. Since the discovery of this parasite at the beginning of the twentieth century …

Oral infection by Trypanosoma cruzi has been the primary cause of recent outbreaks of
acute Chagas' diseases. This route of infection may involve selective binding of the …

Adhesion to extracellular matrix (ECM) proteins plays a crucial role in invasive fungal
diseases. ECM proteins bind to the surface of Paracoccidioides brasiliensis yeast cells in …