Surface patterning of hydrogel biomaterials to probe and direct cell–matrix interactions

BG Munoz‐Robles, I Kopyeva… - Advanced Materials …, 2020 - Wiley Online Library
Due to their mechanical and structural similarity to native tissues, hydrogel biomaterials
have gained tremendous popularity for applications in 3D tissue culture, therapeutic …

Rational design of soft–hard interfaces through bioinspired engineering

H Zhang, Y Ma, Y Wang, L Niu, R Zou, M Zhang, H Liu… - Small, 2023 - Wiley Online Library
Soft–hard tissue interfaces in nature present a diversity of hierarchical transitions in
composition and structure to address the challenge of stress concentrations that would …

Designing Superlubricious Hydrogels from Spontaneous Peroxidation Gradients

AL Chau, CER Edwards, ME Helgeson… - ACS Applied Materials …, 2023 - ACS Publications
Hydrogels are hydrated three-dimensional networks of hydrophilic polymers that are
commonly used in the biomedical industry due to their mechanical and structural tunability …

Fabrication of stiffness gradients of GelMA hydrogels using a 3D printed micromixer

A Lavrentieva, T Fleischhammer… - Macromolecular …, 2020 - Wiley Online Library
Many properties in both healthy and pathological tissues are highly influenced by the
mechanical properties of the extracellular matrix. Stiffness gradient hydrogels are frequently …

[HTML][HTML] Brain organoid-on-a-chip: A next-generation human brain avatar for recapitulating human brain physiology and pathology

J Song, S Bang, N Choi, HN Kim - Biomicrofluidics, 2022 - pubs.aip.org
Neurodegenerative diseases and neurodevelopmental disorders have become increasingly
prevalent; however, the development of new pharmaceuticals to treat these diseases has …

Biomaterials with stiffness gradient for interface tissue engineering

J Cai, J Wang, C Sun, J Dai, C Zhang - Biomedical Materials, 2022 - iopscience.iop.org
Interface tissue engineering is a rapidly growing field that aims to develop engineered tissue
alternates with the goal of promoting integration between multiple tissue types. Engineering …

Visible-Light Stiffness Patterning of GelMA Hydrogels Towards In Vitro Scar Tissue Models

AE Chalard, AW Dixon, AJ Taberner… - Frontiers in Cell and …, 2022 - frontiersin.org
Variations in mechanical properties of the extracellular matrix occurs in various processes,
such as tissue fibrosis. The impact of changes in tissue stiffness on cell behaviour are …

Engineering the cellular mechanical microenvironment–from bulk mechanics to the nanoscale

C Matellan, AE del Río Hernández - Journal of cell science, 2019 - journals.biologists.com
The field of mechanobiology studies how mechanical properties of the extracellular matrix
(ECM), such as stiffness, and other mechanical stimuli regulate cell behaviour. Recent …

Viscous resistance in drop coalescence

MM Rahman, W Lee, A Iyer, SJ Williams - Physics of Fluids, 2019 - pubs.aip.org
Hydrodynamics of drop coalescence has been studied theoretically and numerically by
solving the Navier Stokes equation considering a single fluid after the minimum bridge …

Phospholipid reinforced P (AAm-co-AAc)/Fe3+ hydrogel with ultrahigh strength and superior tribological performance

S Huang, B Wang, X Zhao, S Li, X Liang, R Zeng… - Tribology …, 2022 - Elsevier
With a similar structure as natural cartilage, hydrogels show great potential in repairing
cartilage defect. However, achieving high strength and excellent lubrication is still a …