Supplemental silk protein, sericin, suppresses colon tumorigenesis in 1, 2-dimethylhydrazine-treated mice by reducing oxidative stress and cell proliferation

S Zhaorigetu, M Sasaki, H Watanabe… - Bioscience …, 2001 - Taylor & Francis
This study was done to discover the underlying mechanism of the inhibitory effect of sericin
against colon tumorigenesis. Mice were fed a diet with 30 g/kg sericin for 115 d, and given a …

Animal models for colon carcinogenesis

SE Pories, N Ramchurren, I Summerhayes… - Archives of …, 1993 - jamanetwork.com
Recent identification of genetic alterations in colon polyps and tumors has allowed
construction of a hypothesis for the molecular basis of colon carcinogenesis. The …

1α,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, a Noncalcemic Analogue of 1α,25-Dihydroxyvitamin D3, Inhibits Azoxymethane-induced Colonic …

RK Wali, M Bissonnette, S Khare, J Hart, MD Sitrin… - Cancer research, 1995 - AACR
Vitamin D3 and its metabolites, particularly 1α, 25-dihydroxyvitamin D3 (1α, 25 (OH) 2D3),
have received increasing attention as potential anti-carcinogens in the prevention of cancers …

Immunohistochemical demonstration of c-myc oncogene product in middle ear cholesteatoma

A Holly, M Sittinger, J Bujia - European Archives of Oto-Rhino-Laryngology, 1995 - Springer
Cholesteatoma epithelium is characterized by a dysregulation with a hyperproliferative
growth and altered differentiation. In a variety of cells c-myc oncogene was found to be …

A new polygenic model for nonfamilial colorectal cancer inheritance based on the genetic architecture of the Azoxymethane-induced mouse model

AC Bissahoyo, Y Xie, L Yang, RS Pearsall, D Lee… - Genetics, 2020 - academic.oup.com
The azoxymethane carcinogen model of non-familial colorectal cancer has been used in
mice to identify six new susceptibility loci and confirm 18 of 24 previous detected …

c-myc protein distribution. Neoplastic tissues of the human colon.

N Tulchin, L Ornstein, N Harpaz, J Guillem… - The American journal …, 1992 - ncbi.nlm.nih.gov
There is an extensive literature documenting the increased or deregulated expression of the
c-myc oncogene in human malignancies. The authors have recently devised a sensitive …

Expression of membrane receptors and (proto) oncogenes during the ontogenic development and neoplastic transformation of the intestinal mucosa

E Chastre, S Emami, C Gespach - Life sciences, 1989 - Elsevier
The functional relationship between membrane receptors involved in signal transduction
and (proto) oncogene expression has been explored during the ontogenic development and …

C-myc protein distribution-mammary adenocarcinomas of mtv/myc transgenic mice

N TULCHIN, FS LEE, L ORNSTEIN… - International …, 1995 - spandidos-publications.com
Transgenic mice have been used to demonstrate that the myc transgene, fused to the
murine mammary tumor virus LTR promoter, leads to development of mammary tumors. To …

Altered differentiation of hepatocytes in a transgenic mouse model of hepatocarcinogenesis

A Enomoto, EP Sandgren… - Toxicologic …, 1998 - journals.sagepub.com
Transgenic mice carrying the SV40 T antigen (TAg) gene, which develop hepatocellular and
biliary cell tumors by 4 mo of age, show ductular structures in the neonatal liver …

Análisis de la participación y cumplimiento de la prueba de cribado en un programa de detección precoz de la neoplasia colorrectal. Influencia de la forma de …

R Courtier Bonafont - 2002 - ddd.uab.cat
Introducción: Fuera de toda duda la utilidad de los programas de screening del Cáncer Colo
Rectal (CCR) basados en la detección de sangre oculta en heces en su misión de …