Tuberculosis (TB) has been the most common opportunistic infection and cause of mortality
among HIV-infected patients, especially in resource-limited countries. Clinical …

The human immunodeficiency virus (HIV) epidemic has led to an increase in the incidence
of tuberculosis globally, particularly in sub-Saharan Africa. Coinfection with HIV leads to …

Anti-tuberculosis drug-induced hepatotoxicity (ATDH) is one of the leading adverse drug
reactions during the course of tuberculosis treatment and poses a considerable challenge to …

Unfavorable treatment outcomes for tuberculosis (TB) treatment might result from altered
plasma exposure to antitubercular drugs in TB patients. The present study investigated the …

Background Implication of pharmacogenetic variations and efavirenz pharmacokinetics in
concomitant efavirenz based antiviral therapy and anti-tubercular drug induced liver injury …

Given that infection with Mycobacterium tuberculosis (Mtb) is the leading cause of death
amongst individuals living with HIV, understanding the complex mechanisms by which Mtb …

Background Post-tuberculosis (TB) sequelae present a significant challenge in the
management of TB survivors, often leading to persistent health issues even after successful …

Liver disease in human immunodeficiency virus (HIV)-infected individuals encompasses the
spectrum from abnormal liver function tests, liver decompensation, with and without …

Background Tuberculosis caused by susceptible mycobacterium tuberculosis strains is
effectively treated by the first-line anti-tuberculosis drugs. However, most antibacterial drugs …

Objectives To evaluate the incidence, type, severity and predictors of antiretroviral and/or
anti-tuberculosis drugs induced liver injury (DILI). Methods A total of 1,060 treatment naive …