Heart failure with preserved ejection fraction: a review

MM Redfield, BA Borlaug - Jama, 2023 - jamanetwork.com
Importance Heart failure with preserved ejection fraction (HFpEF), defined as HF with an EF
of 50% or higher at diagnosis, affects approximately 3 million people in the US and up to 32 …

Heart failure with preserved ejection fraction: JACC scientific statement

BA Borlaug, K Sharma, SJ Shah, JE Ho - Journal of the American College …, 2023 - Elsevier
The incidence and prevalence of heart failure with preserved ejection fraction (HFpEF)
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …

[HTML][HTML] Semaglutide in patients with heart failure with preserved ejection fraction and obesity

MN Kosiborod, SZ Abildstrøm, BA Borlaug… - … England Journal of …, 2023 - Mass Medical Soc
Background Heart failure with preserved ejection fraction is increasing in prevalence and is
associated with a high symptom burden and functional impairment, especially in persons …

The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

ME Nassif, SL Windsor, BA Borlaug, DW Kitzman… - Nature medicine, 2021 - nature.com
Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of
symptoms and functional limitations, and have a poor quality of life. By targeting …

Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets

BA Borlaug, MD Jensen, DW Kitzman… - Cardiovascular …, 2022 - academic.oup.com
Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy–A clinical consensus statement of the …

M Guazzi, M Wilhelm, M Halle… - European journal of …, 2022 - Wiley Online Library
Patients with heart failure with preserved ejection fraction (HFpEF) universally complain of
exercise intolerance and dyspnoea as key clinical correlates. Cardiac as well as …

Supervised exercise training for chronic heart failure with preserved ejection fraction: a scientific statement from the American Heart Association and American College …

V Sachdev, K Sharma, SJ Keteyian, CF Alcain… - Circulation, 2023 - Am Heart Assoc
Heart failure with preserved ejection fraction (HFpEF) is one of the most common forms of
heart failure; its prevalence is increasing, and outcomes are worsening. Affected patients …

Exercise for the prevention of anthracycline-induced functional disability and cardiac dysfunction: the BREXIT study

SJ Foulkes, EJ Howden, MJ Haykowsky, Y Antill… - Circulation, 2023 - Am Heart Assoc
Background: Breast cancer survivors treated with anthracycline-based chemotherapy (AC)
have increased risk of functional limitation and cardiac dysfunction. We conducted a 12 …

Cardiac and metabolic effects of dapagliflozin in heart failure with preserved ejection fraction: the CAMEO-DAPA trial

BA Borlaug, YNV Reddy, A Braun, H Sorimachi… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Sodium-glucose cotransporter-2 inhibitors reduce risk of hospitalization for
heart failure in patients who have heart failure with preserved ejection fraction (HFpEF), but …

Phenomapping in heart failure with preserved ejection fraction: insights, limitations, and future directions

AE Peters, J Tromp, SJ Shah, CSP Lam… - Cardiovascular …, 2022 - academic.oup.com
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity with
complex pathophysiology and manifestations. Phenomapping is the process of applying …