Migraine is a complicated neurological disorder affecting 6% of men and 18% of women
worldwide. Various mechanisms, including neuroinflammation, oxidative stress, altered …

Orofacial pain is a universal predicament, afflicting millions of individuals worldwide.
Research on the molecular mechanisms of orofacial pain has predominately focused on the …

Background While previous genome-wide association studies (GWAS) have identified
multiple risk variants for migraine, there is a lack of evidence about how these variants …

Background Recent data suggest that gene expression profiles of peripheral white blood
cells can reflect changes in the brain. We aimed to analyze the transcriptome of peripheral …

Epidemiology is an essential starting point in understanding the burden of a disease in the
population whether in the United States or worldwide. The epidemiology of migraine has …

Background Migraine attacks might be triggered by a disruption of cerebral homeostasis.
During the interictal period migraine patients are characterized by abnormal sensory …

Background We investigated intracerebral fiber bundles using a tract-based spatial statistics
(TBSS) analysis of diffusion tensor imaging (DTI) data to verify microstructural integrity in …

Background The pathomechanisms underlying migraine are intricate and remain largely
unclear. Initially regarded as a neuronal disorder, migraine research primarily concentrated …

Background Gain-of-function missense mutations in the α1A subunit of neuronal CaV2. 1
channels, which define Familial Hemiplegic Migraine Type 1 (FHM1), result in enhanced …

Background There is a bidirectional relationship between migraine and major depression
disorder (MDD). They likely share important risk genes associated with different cell types in …