The serotonergic system forms a diffuse network within the central nervous system and plays
a significant role in the regulation of mood and cognition. Manipulation of tryptophan levels …

We aimed to evaluate the antidepressant activity of deoiled sunflower seeds (SFS), which
are rich in tryptophan, in our mouse model and explored a possible mechanism of action …

Aspartame, an artificial sweetener, is consumed by millions of people globally. There are
multiple reports of aspartame and its metabolites affecting cognitive functions in animal …

The objective of this work was to select wheat genotypes aiming to increase the essential
amino acids in their grains. The study was carried out in the 2019 crop year, in a randomized …

Introduction A gene–environment interaction between expression genotypes of the
monoamine oxidase A (MAOA) and adverse childhood experience increases the risk of …

Various neurological and psychiatric diseases lead to alterations in cortical serotonergic
activity as one of their underlying processes. However, the electrophysiological implication …

The default mode network (DMN) plays a central role in intrinsic thought processes. Altered
DMN connectivity has been linked to diminished cerebral serotonin synthesis. Diminished …

Abstract Brain serotonin (5-HT) system dysfunction is implicated in depressive disorders and
acute depletion of 5-HT precursor tryptophan has frequently been used to model the …

The ubiquitous tripeptide glutathione (GSH) is a critical component of the endogenous
antioxidant defense system. Tissue GSH concentrations and redox status (GSH/GSSG) are …

Alzheimer's is a neurodegenerative disease characterized by cognitive impairment
commonly associated with mood disorders, which trigger depressive reactions and …