Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

Biogenic silver nanoparticles for targeted cancer therapy and enhancing photodynamic therapy

G Kah, R Chandran, H Abrahamse - Cells, 2023 - mdpi.com
Different conventional therapeutic procedures are utilized globally to manage cancer cases,
yet the mortality rate in patients with cancer remains considerably high. Developments in the …

Design and synthesis of new dihydropyrimidine derivatives with a cytotoxic effect as dual EGFR/VEGFR-2 inhibitors

LH Al-Wahaibi, AM Elshamsy, TFS Ali, BGM Youssif… - ACS …, 2024 - ACS Publications
We developed and synthesized tetrahydropyrimidine derivatives as possible cytotoxic
agents to inhibit EGFR and VEGFR-2 in the present study. Our study completely assesses …

Anti-cancer effects of dietary polyphenols via ROS-mediated pathway with their modulation of microRNAs

Y Yoshioka, T Ohishi, Y Nakamura, R Fukutomi… - Molecules, 2022 - mdpi.com
Consumption of coffee, tea, wine, curry, and soybeans has been linked to a lower risk of
cancer in epidemiological studies. Several cell-based and animal studies have shown that …

[HTML][HTML] Mitochondrial targeting theranostic nanomedicine and molecular biomarkers for efficient cancer diagnosis and therapy

SK Rout, V Priya, A Setia, AK Mehata, S Mohan… - Biomedicine & …, 2022 - Elsevier
Mitochondria play a crucial part in the cell's ability to adapt to the changing
microenvironments and their dysfunction is associated with an extensive array of illnesses …

Oxidative stress induced by Pollonein-LAAO, a new L-amino acid oxidase from Bothrops moojeni venom, prompts prostate tumor spheroid cell death and impairs the …

L Polloni, TR Costa, LP Morais, BC Borges… - Cellular …, 2023 - Elsevier
Cancer cells produce abnormal levels of reactive oxygen species (ROS) that contribute to
promote their malignant phenotype. In this framework, we hypothesized that the change in …

Chemical profiling of marine seaweed Halimeda gracilis using UPLC-ESI-Q-TOF-MSE and evaluation of anticancer activity targeting PI3K/AKT and intrinsic apoptosis …

V Ramalingam, NN Kumar, M Harshavardhan… - Food Research …, 2022 - Elsevier
Marine seaweeds are predominant for nutraceuticals and have been food source since
ancient times and are currently being used in Chinese medicines and Japanese traditional …

Rational design and eco-friendly one-pot multicomponent synthesis of novel ethylidenehydrazineylthiazol-4 (5H)-ones as potential apoptotic inducers targeting wild …

EM Abbass, AA Al-Karmalawy, M Sharaky… - Bioorganic …, 2024 - Elsevier
A novel series of ethylidenehydrazineylthiazol-4 (5H)-ones were synthesized using various
eco-friendly one-pot multicomponent synthetic techniques. The anticancer activity of …

Tetramethylpyrazine: An active ingredient of Chinese herbal medicine with therapeutic potential in acute kidney injury and renal fibrosis

J Li, X Gong - Frontiers in Pharmacology, 2022 - frontiersin.org
As an increasing public health concern worldwide, acute kidney injury (AKI) is characterized
by rapid deterioration of kidney function. Although continuous renal replacement therapy …

Research progress of macromolecules in the prevention and treatment of sepsis

J Su, S Wu, F Zhou, Z Tong - International Journal of Molecular Sciences, 2023 - mdpi.com
Sepsis is associated with high rates of mortality in the intensive care unit and accompanied
by systemic inflammatory reactions, secondary infections, and multiple organ failure …