Metabolic syndrome: updates on pathophysiology and management in 2021

G Fahed, L Aoun, M Bou Zerdan, S Allam… - International journal of …, 2022 - mdpi.com
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of …

F Mach, C Baigent, AL Catapano… - European heart …, 2020 - academic.oup.com
version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials

PM Ridker, DL Bhatt, AD Pradhan, RJ Glynn… - The Lancet, 2023 - thelancet.com
Background Inflammation and hyperlipidaemia jointly contribute to atherothrombotic
disease. However, when people are treated with intensive statin therapy, the relative …

Effect of high-dose omega-3 fatty acids vs corn oil on major adverse cardiovascular events in patients at high cardiovascular risk: the STRENGTH randomized clinical …

SJ Nicholls, AM Lincoff, M Garcia, D Bash… - Jama, 2020 - jamanetwork.com
Importance It remains uncertain whether the omega-3 fatty acids eicosapentaenoic acid
(EPA) and docosahexaenoic acid (DHA) reduce cardiovascular risk. Objective To determine …

The intestinal microbiota fuelling metabolic inflammation

H Tilg, N Zmora, TE Adolph, E Elinav - Nature Reviews Immunology, 2020 - nature.com
Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …

Gut microbiota in hypertension and atherosclerosis: a review

BJH Verhaar, A Prodan, M Nieuwdorp, M Muller - Nutrients, 2020 - mdpi.com
Gut microbiota and its metabolites such as short chain fatty acids (SCFA),
lipopolysaccharides (LPS), and trimethylamine-N-oxide (TMAO) impact cardiovascular …

The neutrophil–lymphocyte ratio and incident atherosclerotic events: analyses from five contemporary randomized trials

NH Adamstein, JG MacFadyen, LM Rose… - European heart …, 2021 - academic.oup.com
Aims The neutrophil–lymphocyte ratio (NLR) is a readily available inflammatory biomarker
that may associate with atherosclerosis and predict cardiovascular (CV) events. The aims of …

Inflammation in atherosclerosis—no longer a theory

P Libby - Clinical chemistry, 2021 - academic.oup.com
Background Inflammation links to atherosclerosis and its complications in various
experimental investigations. Animal studies have implicated numerous inflammatory …

Staging and grading of periodontitis: Framework and proposal of a new classification and case definition

MS Tonetti, H Greenwell… - Journal of …, 2018 - Wiley Online Library
Background Authors were assigned the task to develop case definitions for periodontitis in
the context of the 2017 World Workshop on the Classification of Periodontal and Peri …

Vascular inflammation and oxidative stress: major triggers for cardiovascular disease

S Steven, K Frenis, M Oelze, S Kalinovic… - Oxidative medicine …, 2019 - Wiley Online Library
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …