Papillomavirus infections—a major cause of human cancers

H Zur Hausen - Biochimica et biophysica acta (BBA)-reviews on cancer, 1996 - Elsevier
The papillomavirus family represents a remarkably heterogeneous group of viruses. At
present, 77 distinct genotypes have been identified in humans and partial sequences have …

Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis

H Hausen - Journal of the National Cancer Institute, 2000 - academic.oup.com
During the past 20 years, several types of human papillomaviruses (HPVs) have been
identified that cause specific types of cancers. The etiology of cancer of the cervix has been …

Human papillomavirus immortalization and transformation functions

K Münger, PM Howley - Virus research, 2002 - Elsevier
The high risk HPVs (such as HPV-16 and HPV-18) that are associated with specific
anogenital cancers encode two oncoproteins E6 and E7, which are expressed in the HPV …

[HTML][HTML] The E5 proteins

D DiMaio, LM Petti - Virology, 2013 - Elsevier
The E5 proteins are short transmembrane proteins encoded by many animal and human
papillomaviruses. These proteins display transforming activity in cultured cells and animals …

Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity

CM Hebner, LA Laimins - Reviews in medical virology, 2006 - Wiley Online Library
Human papillomaviruses (HPVs) are small double‐stranded DNA viruses that infect the
cutaneous and mucosal epithelium. Infection by specific HPV types has been linked to the …

Papillomavirus E5: the smallest oncoprotein with many functions

A Venuti, F Paolini, L Nasir, A Corteggio, S Roperto… - Molecular cancer, 2011 - Springer
Papillomaviruses (PVs) are established agents of human and animal cancers. They infect
cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are consistently …

The E5 oncoprotein of human papillomavirus type 16 transforms fibroblasts and effects the downregulation of the epidermal growth factor receptor in keratinocytes

SW Straight, PM Hinkle, RJ Jewers… - Journal of virology, 1993 - Am Soc Microbiol
To determine the function of the E5 open reading frame (ORF) of the human
papillomaviruses (HPVs), rodent fibroblast cell lines were transfected with the E5 ORF of …

Biology of human papillomaviruses

HR McMurray, D Nguyen, TF Westbrook… - International journal …, 2001 - Wiley Online Library
Human papillomaviruses (HPVs) cause squamous cancers of epithelial surfaces, of which
genital cancers are the most common. In this article we have attempted to describe the …

The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associate with the 16-kilodalton pore-forming protein

M Conrad, VJ Bubb, R Schlegel - Journal of virology, 1993 - Am Soc Microbiol
The human papillomavirus (HPV) E5 proteins are predicted from DNA sequence analysis to
be small hydrophobic molecules, and the HPV type 6 (HPV-6) and HPV-11 E5 proteins …

Bovine papillomaviruses, papillomas and cancer in cattle

G Borzacchiello, F Roperto - Veterinary research, 2008 - hal.science
Bovine papillomaviruses (BPV) are DNA oncogenic viruses inducing hyperplastic benign
lesions of both cutaneous and mucosal epithelia in cattle. Ten (BPV 1-10) different viral …