Evidence of disturbed insulin signaling in animal models of Alzheimer's disease
Since glucose reuptake by neurons is mostly independent of insulin, it has been an
intriguing question whether insulin has or not any roles in the brain. Consequently, the …
intriguing question whether insulin has or not any roles in the brain. Consequently, the …
A complex systems view on the current hypotheses of epilepsy pharmacoresistance
G Servilha‐Menezes, N Garcia‐Cairasco - Epilepsia Open, 2022 - Wiley Online Library
Drug‐resistant epilepsy remains to this day as a highly prevalent condition affecting around
one‐third of patients with epilepsy, despite all the research and the development of several …
one‐third of patients with epilepsy, despite all the research and the development of several …
[HTML][HTML] Blueberry supplementation in midlife for dementia risk reduction
R Krikorian, MR Skelton, SS Summer, MD Shidler… - Nutrients, 2022 - mdpi.com
Late-life dementia typically develops over a period of many years beginning in midlife.
Prevalence of metabolic disturbance also accelerates in middle age and is a prominent risk …
Prevalence of metabolic disturbance also accelerates in middle age and is a prominent risk …
Analyzing alternative splicing in Alzheimer's disease postmortem brain: a cell-level perspective
ME Farhadieh, K Ghaedi - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease with no effective cure that attacks
the brain's cells resulting in memory loss and changes in behavior and language skills …
the brain's cells resulting in memory loss and changes in behavior and language skills …
Evolving therapeutic interventions for the management and treatment of Alzheimer's disease
Alzheimer's Disease (AD) patients experience diverse symptoms, including memory loss,
cognitive impairment, behavioral abnormalities, mood changes, and mental issues. The …
cognitive impairment, behavioral abnormalities, mood changes, and mental issues. The …
Radix Rehmanniae Praeparata (Shu Dihuang) exerts neuroprotective effects on ICV-STZ-induced Alzheimer's disease mice through modulation of INSR/IRS-1/AKT …
Y Su, N Liu, R Sun, J Ma, Z Li, P Wang, H Ma… - Frontiers in …, 2023 - frontiersin.org
Radix Rehmanniae Praeparata (RRP, Shu Dihuang in Cinese) is widely used as primal
medicine in Chinese herbal formula for the treatment of Alzheimer's disease (AD). However …
medicine in Chinese herbal formula for the treatment of Alzheimer's disease (AD). However …
From attention-deficit hyperactivity disorder to sporadic Alzheimer's disease—Wnt/mTOR pathways hypothesis
Alzheimer's disease (AD) is the most common neurodegenerative disorder with the majority
of patients classified as sporadic AD (sAD), in which etiopathogenesis remains unresolved …
of patients classified as sporadic AD (sAD), in which etiopathogenesis remains unresolved …
Dimethyl fumarate alleviates adult neurogenesis disruption in hippocampus and olfactory bulb and spatial cognitive deficits induced by intracerebroventricular …
E Kurowska-Rucińska, J Ruciński, D Myślińska… - International Journal of …, 2022 - mdpi.com
The disorder of adult neurogenesis is considered an important mechanism underlying the
learning and memory impairment observed in Alzheimer's disease (AD). The sporadic …
learning and memory impairment observed in Alzheimer's disease (AD). The sporadic …
Metabolic disturbances induced by sleep restriction as potential triggers for Alzheimer's disease
JE García-Aviles, R Méndez-Hernández… - Frontiers in Integrative …, 2021 - frontiersin.org
Sleep has a major role in learning, memory consolidation, and metabolic function. Although
it is known that sleep restriction increases the accumulation of amyloid β peptide (Aβ) and …
it is known that sleep restriction increases the accumulation of amyloid β peptide (Aβ) and …
Insights into Gastrointestinal Redox Dysregulation in a Rat Model of Alzheimer's Disease and the Assessment of the Protective Potential of D-Galactose
J Homolak, K Varvaras, V Sciacca, A Babic Perhoc… - ACS …, 2024 - ACS Publications
Recent evidence suggests that the gut plays a vital role in the development and progression
of Alzheimer's disease (AD) by triggering systemic inflammation and oxidative stress. The …
of Alzheimer's disease (AD) by triggering systemic inflammation and oxidative stress. The …