The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
Cancer detection using nanoparticle-based sensors
This tutorial review surveys the latest achievements in the use of nanoparticles to detect
cancer biomarkers and cancer cells with a focus on optical and electrochemical techniques …
cancer biomarkers and cancer cells with a focus on optical and electrochemical techniques …
Toward a molecular understanding of protein solubility: increased negative surface charge correlates with increased solubility
RM Kramer, VR Shende, N Motl, CN Pace, JM Scholtz - Biophysical journal, 2012 - cell.com
Protein solubility is a problem for many protein chemists, including structural biologists and
developers of protein pharmaceuticals. Knowledge about how intrinsic factors influence …
developers of protein pharmaceuticals. Knowledge about how intrinsic factors influence …
Recent advances in nanomaterials for colorimetric cancer detection
H Wang, T Wu, M Li, Y Tao - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
The early diagnosis of cancer can significantly improve patient survival rates. Colorimetric
methods for real-time naked-eye detection have aroused growing interest owing to their low …
methods for real-time naked-eye detection have aroused growing interest owing to their low …
Surface loops of trypsin-like serine proteases as determinants of function
P Goettig, H Brandstetter, V Magdolen - Biochimie, 2019 - Elsevier
Trypsin and chymotrypsin-like serine proteases from family S1 (clan PA) constitute the
largest protease group in humans and more generally in vertebrates. The prototypes …
largest protease group in humans and more generally in vertebrates. The prototypes …
Electrochemical immunosensor based on hybrid MoS2/Pt@ Au-nanoprism/PDA for simultaneous detection of free and total prostate specific antigen in serum
As important biomarkers for prostate cancer, total prostate specific antigen (tPSA) and free
prostate specific antigen (fPSA) levels in serum play essential roles in early diagnosis. In this …
prostate specific antigen (fPSA) levels in serum play essential roles in early diagnosis. In this …
Screen‐printed electrochemical immunosensors for the detection of cancer and cardiovascular biomarkers
EC Rama, A Costa‐García - Electroanalysis, 2016 - Wiley Online Library
Electrochemical immunosensors (EIs) for the determination of disease biomarkers has
attracted a wide interest due to its high sensitivity, low cost, and possible integration in …
attracted a wide interest due to its high sensitivity, low cost, and possible integration in …
Recent trends in targeted therapy of cancer using graphene oxide-modified multifunctional nanomedicines
N Rahmanian, M Eskandani, J Barar… - Journal of drug …, 2017 - Taylor & Francis
Rapid progresses in nanotechnology fields have led us to use a number of advanced
nanomaterials (NMs) for engineering smart multifunctional nanoparticles …
nanomaterials (NMs) for engineering smart multifunctional nanoparticles …
Anatomy and histology of the lower urinary tract
W Pradidarcheep, C Wallner, NF Dabhoiwala… - Urinary Tract, 2011 - Springer
The function of the lower urinary tract is basically storage of urine in the bladder and the at-
will periodic evacuation of the stored urine. Urinary incontinence is one of the most common …
will periodic evacuation of the stored urine. Urinary incontinence is one of the most common …
Prostate-specific kallikrein-related peptidases and their relation to prostate cancer biology and detection
DLJ Thorek, MJ Evans, SV Carlsson… - Thrombosis and …, 2013 - thieme-connect.com
Kallikreins are a family of serine proteases with a range of tissue-specific and essential
proteolytic functions. Among the best studied are the prostate tissue-specific KLK2 and KLK3 …
proteolytic functions. Among the best studied are the prostate tissue-specific KLK2 and KLK3 …