Pulmonary arterial hypertension: pathogenesis and clinical management

T Thenappan, ML Ormiston, JJ Ryan, SL Archer - Bmj, 2018 - bmj.com
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary …

M Humbert, G Kovacs, MM Hoeper… - European heart …, 2022 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

Prediction of O2/N2 Selectivity in Metal–Organic Frameworks via High-Throughput Computational Screening and Machine Learning

IB Orhan, H Daglar, S Keskin, TC Le… - ACS Applied Materials …, 2021 - ACS Publications
Machine learning (ML), which is becoming an increasingly popular tool in various scientific
fields, also shows the potential to aid in the screening of materials for diverse applications. In …

Effects of interatrial shunt on pulmonary vascular function in heart failure with preserved ejection fraction

M Obokata, YNV Reddy, SJ Shah, DM Kaye… - Journal of the American …, 2019 - jacc.org
Background: Implantation of an interatrial shunt device (IASD) in patients with heart failure
(HF) reduces left atrial hypertension by shunting oxygenated blood to the right heart and …

Hypoxia signaling in cancer: Implications for therapeutic interventions

Y Zhuang, K Liu, Q He, X Gu, C Jiang, J Wu - MedComm, 2023 - Wiley Online Library
Hypoxia is a persistent physiological feature of many different solid tumors and a key driver
of malignancy, and in recent years, it has been recognized as an important target for cancer …

Ventilatory response to exercise in cardiopulmonary disease: the role of chemosensitivity and dead space

J Weatherald, C Sattler, G Garcia… - European Respiratory …, 2018 - Eur Respiratory Soc
The lungs and heart are irrevocably linked in their oxygen (O2) and carbon dioxide (CO2)
transport functions. Functional impairment of the lungs often affects heart function and vice …

[HTML][HTML] Ventilatory efficiency in pulmonary vascular diseases

J Weatherald, B Philipenko, D Montani… - European …, 2021 - Eur Respiratory Soc
Cardiopulmonary exercise testing (CPET) is a frequently used tool in the differential
diagnosis of dyspnoea. Ventilatory inefficiency, defined as high minute ventilation (V′ E) …

Excess ventilation and exertional dyspnoea in heart failure and pulmonary hypertension

JA Neder, DB Phillips, DE O'Donnell… - European Respiratory …, 2022 - Eur Respiratory Soc
Increased ventilation relative to metabolic demands, indicating alveolar hyperventilation
and/or increased physiological dead space (excess ventilation), is a key cause of exertional …

Effect of domiciliary oxygen therapy on exercise capacity and quality of life in patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension: a …

S Ulrich, S Saxer, ED Hasler, EI Schwarz… - European …, 2019 - Eur Respiratory Soc
Study question We investigated whether domiciliary oxygen therapy (DOXT) increases
exercise capacity and quality of life in patients with pulmonary arterial or distal chronic …

General measures and supportive therapy for pulmonary arterial hypertension: Updated recommendations from the Cologne Consensus Conference 2018

E Grünig, N Benjamin, U Krüger, H Kaemmerer… - International journal of …, 2018 - Elsevier
In the summer of 2016, delegates from the German Respiratory Society, the German Society
of Cardiology and the German Society of Pediatric Cardiology met in Cologne, Germany, to …