(4+ 3) Cycloadditions have been widely applied in synthesis, and in this review article, we
summarize some of the more recent applications, including formal (4+ 3) cycloadditions, in …

Total synthesis of natural products has greatly contributed to natural product research,
organic synthesis and drug discovery and development. However, in most cases, the …

Rhamnofolane, tigliane, and daphnane diterpenoids are structurally complex natural
products with multiple oxygen functionalities, making them synthetically challenging. While …

Resiniferatoxin (1) belongs to a daphnane diterpenoid family and has strong agonistic
effects on TRPV1, a transducer of noxious temperature and chemical stimuli. The densely …

From both structural and functional perspectives, the large family of daphnane diterpene
orthoesters (DDOs) represent a truly remarkable class of natural products. As potent lead …

Asymmetric construction of the core of C6, C7-epoxy daphnane diterpenoid orthoesters is
developed through a convergent synthetic strategy. The salient features include a …

The complex ABC‐tricyclic structure of crotophorbolone, a derivative of the tigliane
diterpenoids, was assembled by coupling of simple fragments. The six‐membered C‐ring …

Total syntheses of the reported structures of the rhamnofolane diterpene natural products
curcusones I and J in racemic form were achieved. The synthetic strategy features a novel …

Prostratin, a highly complex diterpene natural product, is a pre-clinical candidate in
developing a cure for HIV-1 infection and also a potent and selective inhibitor of several …

We report a new strategy toward the synthesis of highly functionalized carbazoles via 2-
(silyloxy) pentadienyl cation intermediates, which were generated upon ionization of vinyl …