The mechanical properties of cells have been shown to be useful markers of cell state by the
biophysics community. Here, I highlight clinical and research problems that this label-free …

Intensive care unit (ICU) practitioners and emergency department clinicians are in urgent
need of a major upgrade in their access to accurate and fast microbial diagnosis (Table 1) …

Cell state is often assayed through measurement of biochemical and biophysical markers.
Although biochemical markers have been widely used, intrinsic biophysical markers, such …

Here we report a microfluidics method to enrich physically deformable cells by mechanical
manipulation through artificial microbarriers. Driven by hydrodynamic forces, flexible cells or …

Blood and many other multicomponent suspensions display a segregation behavior in
which different components of the suspension are differentially distributed in the cross …

Leukocyte rolling on endothelial cells and other P-selectin substrates is mediated by P-
selectin binding to P-selectin glycoprotein ligand-1 expressed on the tips of leukocyte …

Aggressive tumors of epithelial origin shed cells that intravasate and become circulating
tumor cells (CTC). The CTCs that are able to survive the stresses encountered in the …

Cell sorting is an essential prerequisite for cell research and has great value in life science
and clinical studies. Among the many microfluidic cell sorting technologies, label-free …

Neutrophil recruitment to sites of inflammation involves neutrophil rolling along the inflamed
endothelium in the presence of shear stress imposed by blood flow. Neutrophil rolling in …

During metastasis, tumor cells need to adapt to their dynamic microenvironment and modify
their mechanical properties in response to both chemical and mechanical stimulation …