The sirtuin family in health and disease

QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Nutrition strategy and life style in polycystic ovary syndrome—Narrative review

M Szczuko, J Kikut, U Szczuko, I Szydłowska… - Nutrients, 2021 - mdpi.com
Here we present an extensive narrative review of the broadly understood modifications to
the lifestyles of women with polycystic ovary syndrome (PCOS). The PubMed database was …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose–response meta-analysis of …

MJ Dehzad, H Ghalandari, M Nouri, M Askarpour - Cytokine, 2023 - Elsevier
Turmeric and its prominent bioactive compound, curcumin, have been the subject of many
investigations with regard to their impact on inflammatory and oxidative balance in the body …

[HTML][HTML] Reactive oxygen species and ovarian diseases: Antioxidant strategies

J Liang, Y Gao, Z Feng, B Zhang, Z Na, D Li - Redox Biology, 2023 - Elsevier
Reactive oxygen species (ROS) are mainly produced in mitochondria and are involved in
various physiological activities of the ovary through signaling and are critical for regulating …

Curcumin in metabolic health and disease

M Jabczyk, J Nowak, B Hudzik… - Nutrients, 2021 - mdpi.com
In recent years, epidemiological studies have suggested that metabolic disorders are
nutritionally dependent. A healthy diet that is rich in polyphenols may be beneficial in the …

Turmeric and curcumin: from traditional to modern medicine

M Akaberi, A Sahebkar, SA Emami - … on Biomarkers and New Targets in …, 2021 - Springer
The rhizome of turmeric (Curcuma longa L.) has been used as an herbal medicine, coloring
agent, spice, and food additive for thousands of years in different parts of the world …

Effects of curcumin supplementation on blood glucose, insulin resistance and androgens in patients with polycystic ovary syndrome: A randomized double-blind …

J Heshmati, A Moini, M Sepidarkish, M Morvaridzadeh… - Phytomedicine, 2021 - Elsevier
Background Curcumin is a biologically active phytochemical ingredient found in turmeric. It
has several pharmacologic effects that might benefit patients with polycystic ovary syndrome …

Curcumin supplementation and human disease: a scoping review of clinical trials

TM Panknin, CL Howe, M Hauer… - International Journal of …, 2023 - mdpi.com
Medicinal properties of turmeric (Curcuma longa L.), a plant used for centuries as an anti-
inflammatory, are attributed to its polyphenolic curcuminoids, where curcumin predominates …

The effect of metformin on polycystic ovary syndrome in overweight women: a systematic review and meta‐analysis of randomized controlled trials

Y Guan, D Wang, H Bu, T Zhao… - International journal of …, 2020 - Wiley Online Library
Objective. Metformin is an important component of PCOS treatment. At present, the effect of
metformin in overweight women with PCOS has not been evaluated. Therefore, we …