Extensive research has shown that interleukin 6 (IL-6) is a multifunctional molecule that is
both proinflammatory and anti-inflammatory, depending on the context. Here, we combine …

Genomic instability is an important driver of ageing. The accumulation of DNA damage is
believed to contribute to ageing by inducing cell death, senescence and tissue dysfunction …

Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a
low-grade state of inflammation and different pathologies. The present review aims to …

The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

Background Patients who have received mechanical ventilation can have prolonged
cognitive impairment for which there is no known treatment. We aimed to establish whether …

Exercise has long been known for its active role in improving physical fitness and sustaining
health. Regular moderate-intensity exercise improves all aspects of human health and is …

Background: Exercise leads to a robust inflammatory response mainly characterized by the
mobilization of leukocytes and an increase in circulating inflammatory mediators produced …

Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …