Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation
Single-stranded DNA (ssDNA) intermediates which emerge during DNA metabolic
processes are shielded by replication protein A (RPA). RPA binds to ssDNA and acts as a …
processes are shielded by replication protein A (RPA). RPA binds to ssDNA and acts as a …
Mei5–Sae3 stabilizes Dmc1 nucleating clusters for efficient Dmc1 assembly on RPA-coated single-stranded DNA
CD Wei, HY Chang, CH Lu, CC Chang… - Nucleic Acids …, 2024 - academic.oup.com
Interhomolog recombination in meiosis requires a meiosis-specific recombinase, Dmc1. In
Saccharomyces cerevisiae, the Mei5–Sae3 complex facilitates the loading of Dmc1 onto the …
Saccharomyces cerevisiae, the Mei5–Sae3 complex facilitates the loading of Dmc1 onto the …
Probing the Modulation in Facilitated Diffusion Guided by DNA-Protein Interactions in Target Search Processes
D Thonnekottu, D CHATTERJEE - Physical Chemistry Chemical …, 2024 - pubs.rsc.org
Many fundamental biophysical processes involving gene regulation and gene editing rely, at
the molecular level, on an intricate methodology of searching and locating the precise target …
the molecular level, on an intricate methodology of searching and locating the precise target …
Wrapping of single-stranded DNA by Replication Protein A and modulation through phosphorylation
Single-stranded DNA (ssDNA) intermediates, which emerge during DNA metabolic
processes are shielded by Replication Protein A (RPA). RPA binds to ssDNA and acts as a …
processes are shielded by Replication Protein A (RPA). RPA binds to ssDNA and acts as a …
Rad52 sorts and stacks Rad51 at the DNA junction to promote homologous recombination
Homologous recombination (HR) repairs double-stranded DNA breaks (DSBs). The DSBs
are resected to yield single-stranded DNA (ssDNA) that are coated by Replication Protein A …
are resected to yield single-stranded DNA (ssDNA) that are coated by Replication Protein A …