Breast cancer is the most malignant tumor in women, and there is no absolute cure for it.
Although treatment modalities including surgery, chemotherapy, and radiotherapy are …

Employing combination therapy has become obligatory in cancer cases exhibiting high
tumor load, chemoresistant tumor population, and advanced disease stages. Realization of …

The application of traditional chemotherapy drugs for lung cancer has obvious limitations,
such as toxic side effects, uncontrolled drug-release, poor bioavailability, and drug …

Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …

Gene therapy promises to revolutionize biomedicine and personalized medicine by
modulating or compensating the expression of abnormal genes. The biggest obstacle for …

Although solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have
been successfully used as drug delivery systems for about 30 years, the usage of these …

Amongst the various microtubule-targeting agents, Docetaxel (DTX) has gained immense
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …

Despite all the advances seen in recent years, the severe adverse effects and low specificity
of conventional chemotherapy are still challenging problems regarding cancer treatment …

Cancer is still a severe threat to the health of people worldwide. Chemotherapy is one of
main therapeutic approaches to combat cancer. However, chemotherapy only has a limited …

Cancer cells have characteristics of acquired and intrinsic resistances to chemotherapy
treatment—due to the hostile tumor microenvironment—that create a significant challenge …