Lesion network mapping for symptom localization: recent developments and future directions

J Joutsa, MD Fox - Current opinion in neurology, 2022 - journals.lww.com
Lesion network mapping can be used to map lesion-induced symptoms to brain circuits
rather than single brain regions. Recent findings have provided insight into long-standing …

When visual metacognition fails: widespread anosognosia for visual deficits

M Michel, Y Gao, M Mazor, I Kletenik… - Trends in Cognitive …, 2024 - cell.com
Anosognosia for visual deficits–cases where significant visual deficits go unnoticed–
challenges the view that our own conscious experiences are what we know best. We review …

Network localization of awareness in visual and motor Anosognosia

I Kletenik, K Gaudet, S Prasad, AL Cohen… - Annals of …, 2023 - Wiley Online Library
Objective Unawareness of a deficit, anosognosia, can occur for visual or motor deficits and
lends insight into awareness itself; however, lesions associated with anosognosia occur in …

Multiple sclerosis lesions that impair memory map to a connected memory circuit

I Kletenik, AL Cohen, BI Glanz, MA Ferguson… - Journal of …, 2023 - Springer
Abstract Background Nearly 1 million Americans are living with multiple sclerosis (MS) and
30–50% will experience memory dysfunction. It remains unclear whether this memory …

[HTML][HTML] In humans, striato-pallido-thalamic projections are largely segregated by their origin in either the striosome-like or matrix-like compartments

AT Funk, AAO Hassan, N Brüggemann… - Frontiers in …, 2023 - frontiersin.org
Cortico-striato-thalamo-cortical (CSTC) loops are fundamental organizing units in
mammalian brains. CSTCs process limbic, associative, and sensorimotor information in …

Lesions causing Alice in Wonderland Syndrome map to a common brain network linking body and size perception

MU Friedrich, EC Baughan, I Kletenik… - Annals of …, 2024 - Wiley Online Library
Objective Alice in Wonderland syndrome (AIWS) profoundly affects human perception of
size and scale, particularly regarding one's own body and the environment. Its …

[HTML][HTML] Functional and structural lesion network mapping in neurological and psychiatric disorders: a systematic review

F Nabizadeh, MH Aarabi - Frontiers in Neurology, 2023 - frontiersin.org
Background The traditional approach to studying the neurobiological mechanisms of brain
disorders and localizing brain function involves identifying brain abnormalities and …

A connectivity model of the anatomic substrates underlying Gerstmann syndrome

QS Shahab, IM Young, NB Dadario… - Brain …, 2022 - academic.oup.com
The Gerstmann syndrome is a constellation of neurological deficits that include agraphia,
acalculia, left–right discrimination and finger agnosia. Despite a growing interest in this …

A neural circuit for spatial orientation derived from brain lesions

M Roseman, U Elias, I Kletenik, MA Ferguson… - Cerebral …, 2024 - academic.oup.com
There is disagreement regarding the major components of the brain network supporting
spatial cognition. To address this issue, we applied a lesion mapping approach to the …

[HTML][HTML] Using causal methods to map symptoms to brain circuits in neurodevelopment disorders: moving from identifying correlates to developing treatments

AL Cohen - Journal of Neurodevelopmental Disorders, 2022 - Springer
A wide variety of model systems and experimental techniques can provide insight into the
structure and function of the human brain in typical development and in neurodevelopmental …