NO donors as the wonder molecules with therapeutic potential: Recent trends and future perspectives
Nitric oxide (NO), an endogenous, free radical, highly unstable, diatomic gaseous molecule,
plays crucial roles in several physiological and pathological processes. It has attracted …
plays crucial roles in several physiological and pathological processes. It has attracted …
Recent advances in iron complexes as potential anticancer agents
The revelation of the anticancer properties of cisplatin has inspired research into metal
complexes for the treatment of cancer. Several second and third generation cisplatin …
complexes for the treatment of cancer. Several second and third generation cisplatin …
Recent advances in the chemistry of iron-based chemotherapeutic agents
The discovery of cisplatin followed by its success in anticancer therapy laid the foundation of
metal-based drug design and development. Further research led to discovery of other …
metal-based drug design and development. Further research led to discovery of other …
Fe in biosynthesis, translocation, and signal transduction of NO: toward bioinorganic engineering of dinitrosyl iron complexes into NO-delivery scaffolds for tissue …
Iron, the most abundant transition metal ion in humans, participates in the biosynthesis,
translocation, signal transduction, and transformation of nitric oxide through its …
translocation, signal transduction, and transformation of nitric oxide through its …
A nitrosyl iron complex with 3.4-dichlorothiophenolyl ligands: synthesis, structures and its reactions with targets–carriers of nitrogen oxide (NO) in vivo
OV Pokidova, VO Novikova, NS Emel'yanova… - Dalton …, 2023 - pubs.rsc.org
In this work, a new binuclear nitrosyl complex with 3.4-dichlorothiophenolyl ligands [Fe2
(SC6H3Cl2) 2 (NO) 4] has been synthesized. Nitrosyl iron complexes (NICs) are systems for …
(SC6H3Cl2) 2 (NO) 4] has been synthesized. Nitrosyl iron complexes (NICs) are systems for …
A new member of the cationic dinitrosyl iron complexes family incorporating N-ethylthiourea is effective against human HeLa and MCF-7 tumor cell lines
NA Sanina, NY Shmatko, DV Korchagin… - Journal of …, 2016 - Taylor & Francis
A new analog of the active site of mononuclear dinitrosyl [1Fe–2S] proteins,[C3N2H8SFe
(NO) 2Cl][Fe (NO) 2 (C3N2H8S) 2]+ Cl−(I), has been synthesized by reacting NO with an …
(NO) 2Cl][Fe (NO) 2 (C3N2H8S) 2]+ Cl−(I), has been synthesized by reacting NO with an …
Binuclear nitrosyl iron complex with 4-acetamidothiophenolyl: Synthesis and study of its decomposition in a system with glutathione and albumin
OV Pokidova, VO Novikova, NS Emel'yanova… - Polyhedron, 2024 - Elsevier
In this work, we synthesized a new binuclear nitrosyl iron complex of the family of Roussin's
red salt ester [Fe 2 (C 8 H 8 NOS) 2 (NO) 4](complex 1) with 4-acetamidothiophenol (a …
red salt ester [Fe 2 (C 8 H 8 NOS) 2 (NO) 4](complex 1) with 4-acetamidothiophenol (a …
Synthetic methodology for preparation of dinitrosyl iron complexes
SL Cho, CJ Liao, TT Lu - JBIC Journal of Biological Inorganic Chemistry, 2019 - Springer
After the first structural characterization of dinuclear dinitrosyl iron complex (DNIC) in 1958
and discovery of natural dinitrosyl iron unit (DNIU)[Fe (NO) 2] in 1964–1965, continued …
and discovery of natural dinitrosyl iron unit (DNIU)[Fe (NO) 2] in 1964–1965, continued …
NO-Donor Iron Nitrosyl Complex with N-Ethylthiourea Ligand Exhibits Selective Toxicity to Glioma A172 Cells
N Sanina, N Shmatko, T Stupina, A Balakina… - Molecules, 2017 - mdpi.com
We studied effects of NO-donor iron nitrosyl complex with N-ethylthiourea ligand (ETM) on
normal or tumor-derived cell lines. ETM was mildly toxic to most cell lines studied except the …
normal or tumor-derived cell lines. ETM was mildly toxic to most cell lines studied except the …
N-Heterocyclic Carbene Iron Complexes as Anticancer Agents: In Vitro and In Vivo Biological Studies
OA Lenis-Rojas, S Cordeiro, M Horta-Meireles… - Molecules, 2021 - mdpi.com
Cisplatin and its derivatives are commonly used in chemotherapeutic treatments of cancer,
even though they suffer from many toxic side effects. The problems that emerge from the use …
even though they suffer from many toxic side effects. The problems that emerge from the use …